Matches in SemOpenAlex for { <https://semopenalex.org/work/W2595302513> ?p ?o ?g. }
- W2595302513 endingPage "22" @default.
- W2595302513 startingPage "13" @default.
- W2595302513 abstract "An entomopathogenic bacterium, Xenorhabdus hominickii ANU101, was isolated from an entomopathogenic nematode, Steinernema monticolum. X. hominickii exhibited significant insecticidal activities at ≥6.6 × 102 colony-forming units per larva against a lepidopteran insect, Spodoptera exigua with hemocoelic injection. The insecticidal activity of X. hominickii was reduced by an addition of arachidonic acid (AA, a catalytic product of PLA2), but enhanced by an addition by dexamethasone (DEX, a specific inhibitor of PLA2). S. exigua could defend the bacterial infection by forming hemocyte nodules. However, live X. hominickii significantly reduced the hemocytic nodulation compared to similar treatment with heat-killed X. hominickii. An addition of AA to live X. hominickii significantly rescued the immunosuppression. X. hominickii also inhibited phenoloxidase activity in hemolymph of S. exigua larvae. Furthermore, the bacteria suppressed gene expressions of antimicrobial peptides, such as attacin-1, attacin-2, defensin, gallerimycin and transferrin-1 of S. exigua. An organic extract of X. hominickii-cultured broth with ethyl acetate possessed oxindole and significantly suppressed hemocyte nodulation. Again, an addition of AA diminished the inhibitory activity of the organic extract against hemocyte nodulation. Oxindole alone inhibited hemocyte nodulation and PLA2 enzyme activity. These results suggest that the entomopathogenicity of X. hominickii comes from its inhibitory activity against eicosanoid biosynthesis of target insects." @default.
- W2595302513 created "2017-03-23" @default.
- W2595302513 creator A5006449664 @default.
- W2595302513 creator A5054452172 @default.
- W2595302513 creator A5065214990 @default.
- W2595302513 creator A5066488967 @default.
- W2595302513 creator A5078570442 @default.
- W2595302513 creator A5084504718 @default.
- W2595302513 date "2017-05-01" @default.
- W2595302513 modified "2023-09-23" @default.
- W2595302513 title "An entomopathogenic bacterium, Xenorhabdus hominickii ANU101, produces oxindole and suppresses host insect immune response by inhibiting eicosanoid biosynthesis" @default.
- W2595302513 cites W1581191873 @default.
- W2595302513 cites W1964835439 @default.
- W2595302513 cites W1971461328 @default.
- W2595302513 cites W1994412703 @default.
- W2595302513 cites W1995905074 @default.
- W2595302513 cites W1996730919 @default.
- W2595302513 cites W2001466227 @default.
- W2595302513 cites W2003587139 @default.
- W2595302513 cites W2003895982 @default.
- W2595302513 cites W2008650569 @default.
- W2595302513 cites W2014130802 @default.
- W2595302513 cites W2015435174 @default.
- W2595302513 cites W2028817208 @default.
- W2595302513 cites W2031269469 @default.
- W2595302513 cites W2033191750 @default.
- W2595302513 cites W2033896601 @default.
- W2595302513 cites W2037508363 @default.
- W2595302513 cites W2040250262 @default.
- W2595302513 cites W2042391724 @default.
- W2595302513 cites W2045956054 @default.
- W2595302513 cites W2058967561 @default.
- W2595302513 cites W2072263901 @default.
- W2595302513 cites W2083021273 @default.
- W2595302513 cites W2083681924 @default.
- W2595302513 cites W2095816577 @default.
- W2595302513 cites W2102517829 @default.
- W2595302513 cites W2102524654 @default.
- W2595302513 cites W2102549002 @default.
- W2595302513 cites W2102678394 @default.
- W2595302513 cites W2105199435 @default.
- W2595302513 cites W2107277218 @default.
- W2595302513 cites W2122303780 @default.
- W2595302513 cites W2125702308 @default.
- W2595302513 cites W2127772679 @default.
- W2595302513 cites W2136317422 @default.
- W2595302513 cites W2163647890 @default.
- W2595302513 cites W2164091324 @default.
- W2595302513 cites W2169554406 @default.
- W2595302513 cites W2198528418 @default.
- W2595302513 cites W2221921102 @default.
- W2595302513 cites W2238813834 @default.
- W2595302513 cites W2298617635 @default.
- W2595302513 cites W2331838351 @default.
- W2595302513 cites W2437036636 @default.
- W2595302513 cites W2586306263 @default.
- W2595302513 cites W4293247451 @default.
- W2595302513 doi "https://doi.org/10.1016/j.jip.2017.03.004" @default.
- W2595302513 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28302381" @default.
- W2595302513 hasPublicationYear "2017" @default.
- W2595302513 type Work @default.
- W2595302513 sameAs 2595302513 @default.
- W2595302513 citedByCount "21" @default.
- W2595302513 countsByYear W25953025132017 @default.
- W2595302513 countsByYear W25953025132018 @default.
- W2595302513 countsByYear W25953025132019 @default.
- W2595302513 countsByYear W25953025132020 @default.
- W2595302513 countsByYear W25953025132021 @default.
- W2595302513 countsByYear W25953025132022 @default.
- W2595302513 countsByYear W25953025132023 @default.
- W2595302513 crossrefType "journal-article" @default.
- W2595302513 hasAuthorship W2595302513A5006449664 @default.
- W2595302513 hasAuthorship W2595302513A5054452172 @default.
- W2595302513 hasAuthorship W2595302513A5065214990 @default.
- W2595302513 hasAuthorship W2595302513A5066488967 @default.
- W2595302513 hasAuthorship W2595302513A5078570442 @default.
- W2595302513 hasAuthorship W2595302513A5084504718 @default.
- W2595302513 hasConcept C100068826 @default.
- W2595302513 hasConcept C104317684 @default.
- W2595302513 hasConcept C173758957 @default.
- W2595302513 hasConcept C2777773057 @default.
- W2595302513 hasConcept C2778457844 @default.
- W2595302513 hasConcept C2780473643 @default.
- W2595302513 hasConcept C40767141 @default.
- W2595302513 hasConcept C523546767 @default.
- W2595302513 hasConcept C54355233 @default.
- W2595302513 hasConcept C55493867 @default.
- W2595302513 hasConcept C59822182 @default.
- W2595302513 hasConcept C86803240 @default.
- W2595302513 hasConcept C89423630 @default.
- W2595302513 hasConceptScore W2595302513C100068826 @default.
- W2595302513 hasConceptScore W2595302513C104317684 @default.
- W2595302513 hasConceptScore W2595302513C173758957 @default.
- W2595302513 hasConceptScore W2595302513C2777773057 @default.
- W2595302513 hasConceptScore W2595302513C2778457844 @default.
- W2595302513 hasConceptScore W2595302513C2780473643 @default.
- W2595302513 hasConceptScore W2595302513C40767141 @default.
- W2595302513 hasConceptScore W2595302513C523546767 @default.