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• W2595369732 abstract "Peripheral blood mononuclear cells (PBMCs) were collected from a clinically characterized patient with autism spectrum disorder (ASD). The PMBCs were reprogrammed with the human OSKM transcription factors using the Sendai-virus delivery system. The pluripotency of transgene-free iPSCs was verified by immunocytochemistry for pluripotency markers and by spontaneous in vitro differentiation towards the 3 germ layers. Furthermore, the iPSC line showed normal karyotype. Our model might offer a good platform to study the pathomechanism of ASD, also for drug testing, early biomarker discovery and gene therapy studies." @default.
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• W2595369732 date "2017-05-01" @default.
• W2595369732 modified "2023-10-16" @default.
• W2595369732 title "Establishment of an induced pluripotent stem cell (iPSC) line from a 9-year old male with autism spectrum disorder (ASD)" @default.
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• W2595369732 doi "https://doi.org/10.1016/j.scr.2017.03.013" @default.
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