FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2595493885> ?p ?o ?g. }

• W2595493885 abstract "Investigations of activin family proteins as serum biomarkers for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). CFS/ME is a disease with complex, wide-ranging symptoms, featuring persistent fatigue of 6 months or longer, particularly post exertion. No definitive biomarkers are available. A cross-sectional, observational study of CFS/ME patients fulfilling the 2003 Canadian Consensus Criteria, in parallel with healthy non-fatigued controls, was conducted. Comparisons with a previously defined activin reference population were also performed. For the total study cohort the age range was 18–65 years with a female: male participant ratio of greater than 3:1. All participants were assessed via a primary care community clinic. Blood samples were collected for pathology testing after physical examination and orthostatic intolerance assessment. Cytokines, activin A, activin B and follistatin were also measured in sera from these samples. All data were compared between the CFS/ME and control cohorts, with the activins and follistatin also compared with previously defined reference intervals. Serum activin B levels for CFS/ME participants were significantly elevated when compared to the study controls, as well as the established reference interval. Serum activin A and follistatin were within their normal ranges. All routine and special pathology markers were within the normal laboratory reference intervals for the total study cohort, with no significant differences detected between CFS/ME and control groups. Also, no significant differences were detected for IL-2, IL-4, IL-6, IL-10, IL-17A, TNF or IFN-gamma. Elevated activin B levels together with normal activin A levels identified patients with the diagnostic symptoms of CFS/ME, thus providing a novel serum based test. The activins have multiple physiological roles and capture the diverse array of symptoms experienced by CFS/ME patients." @default.
• W2595493885 created "2017-03-23" @default.
• W2595493885 creator A5018033836 @default.
• W2595493885 creator A5022826774 @default.
• W2595493885 creator A5024131640 @default.
• W2595493885 creator A5041591478 @default.
• W2595493885 creator A5042364212 @default.
• W2595493885 creator A5055304826 @default.
• W2595493885 creator A5060476085 @default.
• W2595493885 date "2017-03-16" @default.
• W2595493885 modified "2023-09-24" @default.
• W2595493885 title "Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: a cross sectional study" @default.
• W2595493885 cites W1567477433 @default.
• W2595493885 cites W1930122810 @default.
• W2595493885 cites W1934388450 @default.
• W2595493885 cites W1994696630 @default.
• W2595493885 cites W1997001753 @default.
• W2595493885 cites W2007757724 @default.
• W2595493885 cites W2008087869 @default.
• W2595493885 cites W2029736131 @default.
• W2595493885 cites W2041712066 @default.
• W2595493885 cites W2044967445 @default.
• W2595493885 cites W2046502802 @default.
• W2595493885 cites W2050298672 @default.
• W2595493885 cites W2053207886 @default.
• W2595493885 cites W2060599764 @default.
• W2595493885 cites W2071802927 @default.
• W2595493885 cites W2073748990 @default.
• W2595493885 cites W2075860873 @default.
• W2595493885 cites W2077976748 @default.
• W2595493885 cites W2085755944 @default.
• W2595493885 cites W2098287790 @default.
• W2595493885 cites W2102368545 @default.
• W2595493885 cites W2106448293 @default.
• W2595493885 cites W2106962555 @default.
• W2595493885 cites W2108645449 @default.
• W2595493885 cites W2109119251 @default.
• W2595493885 cites W2114048115 @default.
• W2595493885 cites W2116310706 @default.
• W2595493885 cites W2126610705 @default.
• W2595493885 cites W2152816976 @default.
• W2595493885 cites W2155596333 @default.
• W2595493885 cites W2160770442 @default.
• W2595493885 cites W2168833309 @default.
• W2595493885 cites W2287383446 @default.
• W2595493885 cites W2416246740 @default.
• W2595493885 doi "https://doi.org/10.1186/s12967-017-1161-4" @default.
• W2595493885 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5353946" @default.
• W2595493885 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28302133" @default.
• W2595493885 hasPublicationYear "2017" @default.
• W2595493885 type Work @default.
• W2595493885 sameAs 2595493885 @default.
• W2595493885 citedByCount "21" @default.
• W2595493885 countsByYear W25954938852017 @default.
• W2595493885 countsByYear W25954938852018 @default.
• W2595493885 countsByYear W25954938852019 @default.
• W2595493885 countsByYear W25954938852020 @default.
• W2595493885 countsByYear W25954938852021 @default.
• W2595493885 countsByYear W25954938852022 @default.
• W2595493885 countsByYear W25954938852023 @default.
• W2595493885 crossrefType "journal-article" @default.
• W2595493885 hasAuthorship W2595493885A5018033836 @default.
• W2595493885 hasAuthorship W2595493885A5022826774 @default.
• W2595493885 hasAuthorship W2595493885A5024131640 @default.
• W2595493885 hasAuthorship W2595493885A5041591478 @default.
• W2595493885 hasAuthorship W2595493885A5042364212 @default.
• W2595493885 hasAuthorship W2595493885A5055304826 @default.
• W2595493885 hasAuthorship W2595493885A5060476085 @default.
• W2595493885 hasBestOaLocation W25954938851 @default.
• W2595493885 hasConcept C126322002 @default.
• W2595493885 hasConcept C142052008 @default.
• W2595493885 hasConcept C142724271 @default.
• W2595493885 hasConcept C201903717 @default.
• W2595493885 hasConcept C203014093 @default.
• W2595493885 hasConcept C2778831791 @default.
• W2595493885 hasConcept C2779566273 @default.
• W2595493885 hasConcept C2781197716 @default.
• W2595493885 hasConcept C2908647359 @default.
• W2595493885 hasConcept C42407357 @default.
• W2595493885 hasConcept C55493867 @default.
• W2595493885 hasConcept C71924100 @default.
• W2595493885 hasConcept C72563966 @default.
• W2595493885 hasConcept C86803240 @default.
• W2595493885 hasConcept C99454951 @default.
• W2595493885 hasConceptScore W2595493885C126322002 @default.
• W2595493885 hasConceptScore W2595493885C142052008 @default.
• W2595493885 hasConceptScore W2595493885C142724271 @default.
• W2595493885 hasConceptScore W2595493885C201903717 @default.
• W2595493885 hasConceptScore W2595493885C203014093 @default.
• W2595493885 hasConceptScore W2595493885C2778831791 @default.
• W2595493885 hasConceptScore W2595493885C2779566273 @default.
• W2595493885 hasConceptScore W2595493885C2781197716 @default.
• W2595493885 hasConceptScore W2595493885C2908647359 @default.
• W2595493885 hasConceptScore W2595493885C42407357 @default.
• W2595493885 hasConceptScore W2595493885C55493867 @default.
• W2595493885 hasConceptScore W2595493885C71924100 @default.
• W2595493885 hasConceptScore W2595493885C72563966 @default.
• W2595493885 hasConceptScore W2595493885C86803240 @default.
• W2595493885 hasConceptScore W2595493885C99454951 @default.
• W2595493885 hasFunder F4320334705 @default.

• next