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- W2595667698 abstract "Carbapenems are among the most commonly used and the most efficient antibiotics since they are relatively resistant to hydrolysis by most β-lactamases, they target penicillin-binding proteins, and generally have broad-spectrum antibacterial effect. In this review, we described the initial discovery and development of carbapenems, chemical characteristics, in vitro/in vivo activities, resistance studies, and clinical investigations for traditional carbapenem antibiotics in the market; imipenem-cilastatin, meropenem, ertapenem, doripenem, biapenem, panipenem/betamipron in addition to newer carbapenems such as razupenem, tebipenem, tomopenem, and sanfetrinem. We focused on the literature published from 2010 to 2016." @default.
- W2595667698 created "2017-03-23" @default.
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- W2595667698 date "2017-05-01" @default.
- W2595667698 modified "2023-10-17" @default.
- W2595667698 title "Recent updates of carbapenem antibiotics" @default.
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- W2595667698 doi "https://doi.org/10.1016/j.ejmech.2017.03.022" @default.
- W2595667698 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28324783" @default.
- W2595667698 hasPublicationYear "2017" @default.
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