FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2595683614> ?p ?o ?g. }

• W2595683614 endingPage "135" @default.
• W2595683614 startingPage "129" @default.
• W2595683614 abstract "Pseudomonas aeruginosa is an opportunistic pathogen, enable of causing infections especially in immunocompromised patients. Recently many isolates developed multiple drug resistance, resulting in treatment failure in serious infections. In this study, the effect of tobramycin incorporated with bismuth-ethanedithiol loaded on niosomes on the quorum sensing and biofilm production by P. aeruginosa was evaluated. Thin layer hydration method with cholesterol (30%), Span 40 and Tween 40 were used to make niosomes. The physical properties and particle size of the niosomes were investigated. Micro dilution method was used to determine the Minimum Inhibitory Concentration (MIC) for tobramycin, niosomal tobramycin, bismuth ethanedithiol, niosomal bismuth ethanedithiol, tobramycin incorporated with bismuth-ethanedithiol and niosomal tobramycin incorporated with bismuth-ethanedithiol. Biofilm formation was evaluated using microtiter plate. The effect of different combination on N-acyl homoserine lactone (AHL) production was evaluated in presence of Agrobacterium tumefaciens strain (GV3101). The best combination inhibiting the growth of various strains of P. aeruginosa were niosomal tobramycin and niosomal tobramycin incorporated with bismuth-ethanedithiol which reduced the MIC of tobramycin significantly. Sub-MIC concentration of these compounds reduced the rate of biofilm formation 80% lower than the untreated bacteria, and effectively inhibited the production of AHL molecule. The prepared formulations containing non-ionic surfactants, can kept the drug and gradually release it. Encapsulation of tobramycin in combination with bismuth-ethanedithiol in niosome had the ability to reduce the MIC of tobramycin and effectively inhibiting the biofilm formation. These combinations can be used as an excellent combination for further evaluation for treatment of infections caused by MDR isolates of P. aeruginosa." @default.
• W2595683614 created "2017-03-23" @default.
• W2595683614 creator A5027358963 @default.
• W2595683614 creator A5047518707 @default.
• W2595683614 creator A5062187045 @default.
• W2595683614 creator A5081804018 @default.
• W2595683614 date "2017-06-01" @default.
• W2595683614 modified "2023-10-16" @default.
• W2595683614 title "The effect of tobramycin incorporated with bismuth-ethanedithiol loaded on niosomes on the quorum sensing and biofilm formation of Pseudomonas aeruginosa" @default.
• W2595683614 cites W1964466122 @default.
• W2595683614 cites W1968601352 @default.
• W2595683614 cites W1978184903 @default.
• W2595683614 cites W1996442931 @default.
• W2595683614 cites W1998020561 @default.
• W2595683614 cites W2000753279 @default.
• W2595683614 cites W2010177488 @default.
• W2595683614 cites W2013293890 @default.
• W2595683614 cites W2020018901 @default.
• W2595683614 cites W2021165136 @default.
• W2595683614 cites W2034280827 @default.
• W2595683614 cites W2054733503 @default.
• W2595683614 cites W2056089287 @default.
• W2595683614 cites W2083456954 @default.
• W2595683614 cites W2097199878 @default.
• W2595683614 cites W2097675279 @default.
• W2595683614 cites W2098189029 @default.
• W2595683614 cites W2111192867 @default.
• W2595683614 cites W2116929184 @default.
• W2595683614 cites W2117185308 @default.
• W2595683614 cites W2125059211 @default.
• W2595683614 cites W2131727615 @default.
• W2595683614 cites W2131927792 @default.
• W2595683614 cites W2142963330 @default.
• W2595683614 cites W2155439177 @default.
• W2595683614 cites W2163903634 @default.
• W2595683614 doi "https://doi.org/10.1016/j.micpath.2017.03.014" @default.
• W2595683614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28323149" @default.
• W2595683614 hasPublicationYear "2017" @default.
• W2595683614 type Work @default.
• W2595683614 sameAs 2595683614 @default.
• W2595683614 citedByCount "22" @default.
• W2595683614 countsByYear W25956836142017 @default.
• W2595683614 countsByYear W25956836142018 @default.
• W2595683614 countsByYear W25956836142019 @default.
• W2595683614 countsByYear W25956836142020 @default.
• W2595683614 countsByYear W25956836142021 @default.
• W2595683614 countsByYear W25956836142022 @default.
• W2595683614 countsByYear W25956836142023 @default.
• W2595683614 crossrefType "journal-article" @default.
• W2595683614 hasAuthorship W2595683614A5027358963 @default.
• W2595683614 hasAuthorship W2595683614A5047518707 @default.
• W2595683614 hasAuthorship W2595683614A5062187045 @default.
• W2595683614 hasAuthorship W2595683614A5081804018 @default.
• W2595683614 hasConcept C118687296 @default.
• W2595683614 hasConcept C130316041 @default.
• W2595683614 hasConcept C176947019 @default.
• W2595683614 hasConcept C185592680 @default.
• W2595683614 hasConcept C2777637488 @default.
• W2595683614 hasConcept C2778974779 @default.
• W2595683614 hasConcept C41625074 @default.
• W2595683614 hasConcept C4937899 @default.
• W2595683614 hasConcept C523546767 @default.
• W2595683614 hasConcept C54355233 @default.
• W2595683614 hasConcept C55493867 @default.
• W2595683614 hasConcept C58123911 @default.
• W2595683614 hasConcept C72918618 @default.
• W2595683614 hasConcept C86803240 @default.
• W2595683614 hasConcept C89423630 @default.
• W2595683614 hasConceptScore W2595683614C118687296 @default.
• W2595683614 hasConceptScore W2595683614C130316041 @default.
• W2595683614 hasConceptScore W2595683614C176947019 @default.
• W2595683614 hasConceptScore W2595683614C185592680 @default.
• W2595683614 hasConceptScore W2595683614C2777637488 @default.
• W2595683614 hasConceptScore W2595683614C2778974779 @default.
• W2595683614 hasConceptScore W2595683614C41625074 @default.
• W2595683614 hasConceptScore W2595683614C4937899 @default.
• W2595683614 hasConceptScore W2595683614C523546767 @default.
• W2595683614 hasConceptScore W2595683614C54355233 @default.
• W2595683614 hasConceptScore W2595683614C55493867 @default.
• W2595683614 hasConceptScore W2595683614C58123911 @default.
• W2595683614 hasConceptScore W2595683614C72918618 @default.
• W2595683614 hasConceptScore W2595683614C86803240 @default.
• W2595683614 hasConceptScore W2595683614C89423630 @default.
• W2595683614 hasLocation W25956836141 @default.
• W2595683614 hasLocation W25956836142 @default.
• W2595683614 hasOpenAccess W2595683614 @default.
• W2595683614 hasPrimaryLocation W25956836141 @default.
• W2595683614 hasRelatedWork W2016544483 @default.
• W2595683614 hasRelatedWork W2025231699 @default.
• W2595683614 hasRelatedWork W2056089287 @default.
• W2595683614 hasRelatedWork W2131903790 @default.
• W2595683614 hasRelatedWork W2146054291 @default.
• W2595683614 hasRelatedWork W2197362931 @default.
• W2595683614 hasRelatedWork W2964010063 @default.
• W2595683614 hasRelatedWork W3094496711 @default.
• W2595683614 hasRelatedWork W3097647920 @default.
• W2595683614 hasRelatedWork W4220725088 @default.
• W2595683614 hasVolume "107" @default.

• next