Matches in SemOpenAlex for { <https://semopenalex.org/work/W259575300> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W259575300 endingPage "44" @default.
- W259575300 startingPage "28" @default.
- W259575300 abstract "A comprehensive overview on the course of hepatitis C is not available despite the many studies published. The aim was to review the course and prognostic variables of untreated hepatitis C.English-language articles published between January 1989 and December 1997 were identified and data extracted to answer predefined relevant questions.Median chronicization rate, mostly assessed in transfusion-associated hepatitis, was 67%. In retrospective studies, the interval between date of infection and diagnosis of cirrhosis or hepatocellular carcinoma was 20-40 years. Median progression rate from chronic hepatitis to cirrhosis was 27.9% after 8-12 years. Studies obtaining this figure included selected groups of patients and could reflect the worst prognostic segment of the disease. The course of hepatitis C virus infection may be more favourable: cirrhosis rarely or never occurred in young females infected by con-taminated anti-D-immunglobulins; hepatitis was histologically mild in most hepatitis C virus-RNA positive subjects with normal or near normal transminases, predicting non-progressive or very slowly progressive disease; in a population survey from Italy, among 170 infected subjects only 4% had raised transaminases, and none overt liver disease. Increasing age, histological severity, alcohol, possibly male sex and liver iron content were predictors of cirrhosis or increased fibrosis.Chronicization rate of hepatitis C virus infection is very high. Hepatitis C virus infection can result in a wide prognostic spectrum of liver disease, ranging from cirrhosis and hepatocellular carcinoma to subclinical, nonprogressive disease. Cofactors such as alcohol excess are important in determining the outcome of hepatitis C virus-related chronic liver disease." @default.
- W259575300 created "2016-06-24" @default.
- W259575300 creator A5013334772 @default.
- W259575300 creator A5014826030 @default.
- W259575300 creator A5035276390 @default.
- W259575300 creator A5039568731 @default.
- W259575300 creator A5042737027 @default.
- W259575300 creator A5088437026 @default.
- W259575300 date "1999-03-26" @default.
- W259575300 modified "2023-10-05" @default.
- W259575300 title "Natural history of chronic hepatitis C." @default.
- W259575300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10091101" @default.
- W259575300 hasPublicationYear "1999" @default.
- W259575300 type Work @default.
- W259575300 sameAs 259575300 @default.
- W259575300 citedByCount "41" @default.
- W259575300 countsByYear W2595753002014 @default.
- W259575300 countsByYear W2595753002016 @default.
- W259575300 countsByYear W2595753002017 @default.
- W259575300 countsByYear W2595753002021 @default.
- W259575300 crossrefType "journal-article" @default.
- W259575300 hasAuthorship W259575300A5013334772 @default.
- W259575300 hasAuthorship W259575300A5014826030 @default.
- W259575300 hasAuthorship W259575300A5035276390 @default.
- W259575300 hasAuthorship W259575300A5039568731 @default.
- W259575300 hasAuthorship W259575300A5042737027 @default.
- W259575300 hasAuthorship W259575300A5088437026 @default.
- W259575300 hasConcept C113280763 @default.
- W259575300 hasConcept C126322002 @default.
- W259575300 hasConcept C163276114 @default.
- W259575300 hasConcept C203014093 @default.
- W259575300 hasConcept C2522874641 @default.
- W259575300 hasConcept C2776029263 @default.
- W259575300 hasConcept C2776408679 @default.
- W259575300 hasConcept C2776455275 @default.
- W259575300 hasConcept C2777075537 @default.
- W259575300 hasConcept C2777214474 @default.
- W259575300 hasConcept C2778019345 @default.
- W259575300 hasConcept C2908647359 @default.
- W259575300 hasConcept C71924100 @default.
- W259575300 hasConcept C90924648 @default.
- W259575300 hasConcept C99454951 @default.
- W259575300 hasConceptScore W259575300C113280763 @default.
- W259575300 hasConceptScore W259575300C126322002 @default.
- W259575300 hasConceptScore W259575300C163276114 @default.
- W259575300 hasConceptScore W259575300C203014093 @default.
- W259575300 hasConceptScore W259575300C2522874641 @default.
- W259575300 hasConceptScore W259575300C2776029263 @default.
- W259575300 hasConceptScore W259575300C2776408679 @default.
- W259575300 hasConceptScore W259575300C2776455275 @default.
- W259575300 hasConceptScore W259575300C2777075537 @default.
- W259575300 hasConceptScore W259575300C2777214474 @default.
- W259575300 hasConceptScore W259575300C2778019345 @default.
- W259575300 hasConceptScore W259575300C2908647359 @default.
- W259575300 hasConceptScore W259575300C71924100 @default.
- W259575300 hasConceptScore W259575300C90924648 @default.
- W259575300 hasConceptScore W259575300C99454951 @default.
- W259575300 hasIssue "1" @default.
- W259575300 hasLocation W2595753001 @default.
- W259575300 hasOpenAccess W259575300 @default.
- W259575300 hasPrimaryLocation W2595753001 @default.
- W259575300 hasRelatedWork W1967442145 @default.
- W259575300 hasRelatedWork W2013730096 @default.
- W259575300 hasRelatedWork W2047888069 @default.
- W259575300 hasRelatedWork W2076945923 @default.
- W259575300 hasRelatedWork W2085600385 @default.
- W259575300 hasRelatedWork W2146236851 @default.
- W259575300 hasRelatedWork W2409860371 @default.
- W259575300 hasRelatedWork W259575300 @default.
- W259575300 hasRelatedWork W3032199483 @default.
- W259575300 hasRelatedWork W3152171701 @default.
- W259575300 hasVolume "31" @default.
- W259575300 isParatext "false" @default.
- W259575300 isRetracted "false" @default.
- W259575300 magId "259575300" @default.
- W259575300 workType "article" @default.