FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2595755764> ?p ?o ?g. }

• W2595755764 endingPage "226" @default.
• W2595755764 startingPage "215" @default.
• W2595755764 abstract "The purpose of this study is to characterize controlled release matrix tablets of captopril and to find out the physicochemical properties that have an effect on the mucoadhesion process. The hydrophilic matrix tablets contain captopril, microcrystalline cellulose, barium sulfate, ascorbic acid, ethylcellulose N100, hydroxypropylmethylcellulose K15M, talc, magnesium stearate and colloidal silicon dioxide. The physicochemical properties of the formulations have been characterized using confocal microscopy, contact angle, and scanning electron microscopy. The potential mucoadhesion capabilities of the formulations were assessed measuring the surface free energy, the polar and dispersive forces, the spreading coefficients, the surface roughness, and the network structure of the hydrophilic matrix tablets. The results show that when the concentration of HPMC K15M increases, the spreading coefficients of polymer over mucus and mucus over polymer are more positive, thus increasing the contact between the matrix tablets with the mucus layer. The formulation that contains 15% of HPMC K15M is the formulation that presents a greater swelling capacity, a greater increase in surface roughness, and larger pores within the matrix. This formulation has a higher chain mobility and more free macromolecular chains able to diffuse in the mucus layer. Therefore, this formulation has the greatest potential mucoadhesion capability." @default.
• W2595755764 created "2017-03-23" @default.
• W2595755764 creator A5001275678 @default.
• W2595755764 creator A5009308437 @default.
• W2595755764 creator A5036047079 @default.
• W2595755764 creator A5053139423 @default.
• W2595755764 creator A5055660802 @default.
• W2595755764 creator A5061448958 @default.
• W2595755764 creator A5064139616 @default.
• W2595755764 creator A5066094127 @default.
• W2595755764 creator A5077201330 @default.
• W2595755764 creator A5086996718 @default.
• W2595755764 creator A5088936665 @default.
• W2595755764 date "2017-12-01" @default.
• W2595755764 modified "2023-10-15" @default.
• W2595755764 title "Formulation and characterization of mucoadhesive controlled release matrix tablets of captopril" @default.
• W2595755764 cites W1841575461 @default.
• W2595755764 cites W1876945131 @default.
• W2595755764 cites W1972255908 @default.
• W2595755764 cites W1979189978 @default.
• W2595755764 cites W1987451124 @default.
• W2595755764 cites W1999120789 @default.
• W2595755764 cites W2004173569 @default.
• W2595755764 cites W2010508362 @default.
• W2595755764 cites W2014864181 @default.
• W2595755764 cites W2014994880 @default.
• W2595755764 cites W2017332118 @default.
• W2595755764 cites W2021978496 @default.
• W2595755764 cites W2026039351 @default.
• W2595755764 cites W2027507514 @default.
• W2595755764 cites W2031608958 @default.
• W2595755764 cites W2036748489 @default.
• W2595755764 cites W2042188843 @default.
• W2595755764 cites W2061358080 @default.
• W2595755764 cites W2076659739 @default.
• W2595755764 cites W2077025851 @default.
• W2595755764 cites W2079535948 @default.
• W2595755764 cites W2122018431 @default.
• W2595755764 cites W2175375867 @default.
• W2595755764 cites W2315980277 @default.
• W2595755764 doi "https://doi.org/10.1016/j.jddst.2017.03.009" @default.
• W2595755764 hasPublicationYear "2017" @default.
• W2595755764 type Work @default.
• W2595755764 sameAs 2595755764 @default.
• W2595755764 citedByCount "7" @default.
• W2595755764 countsByYear W25957557642018 @default.
• W2595755764 countsByYear W25957557642019 @default.
• W2595755764 countsByYear W25957557642020 @default.
• W2595755764 countsByYear W25957557642021 @default.
• W2595755764 crossrefType "journal-article" @default.
• W2595755764 hasAuthorship W2595755764A5001275678 @default.
• W2595755764 hasAuthorship W2595755764A5009308437 @default.
• W2595755764 hasAuthorship W2595755764A5036047079 @default.
• W2595755764 hasAuthorship W2595755764A5053139423 @default.
• W2595755764 hasAuthorship W2595755764A5055660802 @default.
• W2595755764 hasAuthorship W2595755764A5061448958 @default.
• W2595755764 hasAuthorship W2595755764A5064139616 @default.
• W2595755764 hasAuthorship W2595755764A5066094127 @default.
• W2595755764 hasAuthorship W2595755764A5077201330 @default.
• W2595755764 hasAuthorship W2595755764A5086996718 @default.
• W2595755764 hasAuthorship W2595755764A5088936665 @default.
• W2595755764 hasBestOaLocation W25957557642 @default.
• W2595755764 hasConcept C106487976 @default.
• W2595755764 hasConcept C127413603 @default.
• W2595755764 hasConcept C159985019 @default.
• W2595755764 hasConcept C185592680 @default.
• W2595755764 hasConcept C192562407 @default.
• W2595755764 hasConcept C2776634624 @default.
• W2595755764 hasConcept C2778572730 @default.
• W2595755764 hasConcept C2780020223 @default.
• W2595755764 hasConcept C42360764 @default.
• W2595755764 hasConcept C43617362 @default.
• W2595755764 hasConcept C521977710 @default.
• W2595755764 hasConcept C6556556 @default.
• W2595755764 hasConcept C77281830 @default.
• W2595755764 hasConceptScore W2595755764C106487976 @default.
• W2595755764 hasConceptScore W2595755764C127413603 @default.
• W2595755764 hasConceptScore W2595755764C159985019 @default.
• W2595755764 hasConceptScore W2595755764C185592680 @default.
• W2595755764 hasConceptScore W2595755764C192562407 @default.
• W2595755764 hasConceptScore W2595755764C2776634624 @default.
• W2595755764 hasConceptScore W2595755764C2778572730 @default.
• W2595755764 hasConceptScore W2595755764C2780020223 @default.
• W2595755764 hasConceptScore W2595755764C42360764 @default.
• W2595755764 hasConceptScore W2595755764C43617362 @default.
• W2595755764 hasConceptScore W2595755764C521977710 @default.
• W2595755764 hasConceptScore W2595755764C6556556 @default.
• W2595755764 hasConceptScore W2595755764C77281830 @default.
• W2595755764 hasFunder F4320321505 @default.
• W2595755764 hasFunder F4320322930 @default.
• W2595755764 hasLocation W25957557641 @default.
• W2595755764 hasLocation W25957557642 @default.
• W2595755764 hasLocation W25957557643 @default.
• W2595755764 hasOpenAccess W2595755764 @default.
• W2595755764 hasPrimaryLocation W25957557641 @default.
• W2595755764 hasRelatedWork W1573867045 @default.
• W2595755764 hasRelatedWork W2058674497 @default.
• W2595755764 hasRelatedWork W2161314874 @default.

• next