Matches in SemOpenAlex for { <https://semopenalex.org/work/W2596322362> ?p ?o ?g. }
- W2596322362 abstract "Abstract Poor antigenic presentation of tumor tissues and a lack of specific targets currently limit the success of nanoparticle delivery system. Cellular carrier technique has been recently explored extensively as a substitutive or supplement for traditional targeting delivery system. Here, we demonstrate the usage of mesenchymal stem cells (MSCs) loaded with doxorubicin containing polymer nanoparticles in pulmonary melanoma metastases therapy, as a modified technique of targeted delivery system. The characterizations of prepared nanoparticles and MSCs sensitivity to DOX and PLGA-DOX were measured. In vitro tumor tropism, and in vivo distributions of nanoparticles loaded MSCs were also investigated. The findings have demonstrated that, the modified system not only integrates the controlled-release property of nanoparticles but also exhibits tumor tropism and penetrative characteristics of MSCs. Furthermore, the in vitro and in vivo anti-tumor study has demonstrated that drug loaded MSCs had potent efficacy in lung melanoma metastases treatment." @default.
- W2596322362 created "2017-03-23" @default.
- W2596322362 creator A5003579017 @default.
- W2596322362 creator A5003706548 @default.
- W2596322362 creator A5007180092 @default.
- W2596322362 creator A5014131230 @default.
- W2596322362 creator A5056729991 @default.
- W2596322362 creator A5060608811 @default.
- W2596322362 creator A5064303233 @default.
- W2596322362 creator A5066738004 @default.
- W2596322362 creator A5074742106 @default.
- W2596322362 creator A5075346684 @default.
- W2596322362 creator A5080370820 @default.
- W2596322362 creator A5087989030 @default.
- W2596322362 date "2017-03-17" @default.
- W2596322362 modified "2023-10-16" @default.
- W2596322362 title "Targeted delivery of doxorubicin by nano-loaded mesenchymal stem cells for lung melanoma metastases therapy" @default.
- W2596322362 cites W1265966323 @default.
- W2596322362 cites W1914131546 @default.
- W2596322362 cites W1966263947 @default.
- W2596322362 cites W1975150426 @default.
- W2596322362 cites W1984005906 @default.
- W2596322362 cites W1987633286 @default.
- W2596322362 cites W1991105889 @default.
- W2596322362 cites W1994351166 @default.
- W2596322362 cites W2011271265 @default.
- W2596322362 cites W2015869298 @default.
- W2596322362 cites W2017950444 @default.
- W2596322362 cites W2027353500 @default.
- W2596322362 cites W2031114068 @default.
- W2596322362 cites W2039100374 @default.
- W2596322362 cites W2041454553 @default.
- W2596322362 cites W2042201808 @default.
- W2596322362 cites W2042469549 @default.
- W2596322362 cites W2061760711 @default.
- W2596322362 cites W2078147660 @default.
- W2596322362 cites W2087914018 @default.
- W2596322362 cites W2090038094 @default.
- W2596322362 cites W2093759755 @default.
- W2596322362 cites W2094155824 @default.
- W2596322362 cites W2097942616 @default.
- W2596322362 cites W2113358240 @default.
- W2596322362 cites W2116216122 @default.
- W2596322362 cites W2122421905 @default.
- W2596322362 cites W2124723818 @default.
- W2596322362 cites W2127228308 @default.
- W2596322362 cites W2141811329 @default.
- W2596322362 cites W2165264327 @default.
- W2596322362 cites W2167806590 @default.
- W2596322362 cites W2214752215 @default.
- W2596322362 cites W2328292603 @default.
- W2596322362 cites W2917837889 @default.
- W2596322362 cites W598202522 @default.
- W2596322362 doi "https://doi.org/10.1038/srep44758" @default.
- W2596322362 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5355993" @default.
- W2596322362 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28303966" @default.
- W2596322362 hasPublicationYear "2017" @default.
- W2596322362 type Work @default.
- W2596322362 sameAs 2596322362 @default.
- W2596322362 citedByCount "60" @default.
- W2596322362 countsByYear W25963223622017 @default.
- W2596322362 countsByYear W25963223622018 @default.
- W2596322362 countsByYear W25963223622019 @default.
- W2596322362 countsByYear W25963223622020 @default.
- W2596322362 countsByYear W25963223622021 @default.
- W2596322362 countsByYear W25963223622022 @default.
- W2596322362 countsByYear W25963223622023 @default.
- W2596322362 crossrefType "journal-article" @default.
- W2596322362 hasAuthorship W2596322362A5003579017 @default.
- W2596322362 hasAuthorship W2596322362A5003706548 @default.
- W2596322362 hasAuthorship W2596322362A5007180092 @default.
- W2596322362 hasAuthorship W2596322362A5014131230 @default.
- W2596322362 hasAuthorship W2596322362A5056729991 @default.
- W2596322362 hasAuthorship W2596322362A5060608811 @default.
- W2596322362 hasAuthorship W2596322362A5064303233 @default.
- W2596322362 hasAuthorship W2596322362A5066738004 @default.
- W2596322362 hasAuthorship W2596322362A5074742106 @default.
- W2596322362 hasAuthorship W2596322362A5075346684 @default.
- W2596322362 hasAuthorship W2596322362A5080370820 @default.
- W2596322362 hasAuthorship W2596322362A5087989030 @default.
- W2596322362 hasBestOaLocation W25963223621 @default.
- W2596322362 hasConcept C121608353 @default.
- W2596322362 hasConcept C126322002 @default.
- W2596322362 hasConcept C142724271 @default.
- W2596322362 hasConcept C150903083 @default.
- W2596322362 hasConcept C171250308 @default.
- W2596322362 hasConcept C185592680 @default.
- W2596322362 hasConcept C192562407 @default.
- W2596322362 hasConcept C198826908 @default.
- W2596322362 hasConcept C202751555 @default.
- W2596322362 hasConcept C203014093 @default.
- W2596322362 hasConcept C207001950 @default.
- W2596322362 hasConcept C2522874641 @default.
- W2596322362 hasConcept C2776694085 @default.
- W2596322362 hasConcept C2777658100 @default.
- W2596322362 hasConcept C2779820397 @default.
- W2596322362 hasConcept C2781230642 @default.
- W2596322362 hasConcept C2781303535 @default.
- W2596322362 hasConcept C35693153 @default.
- W2596322362 hasConcept C502942594 @default.