Matches in SemOpenAlex for { <https://semopenalex.org/work/W2596604530> ?p ?o ?g. }
- W2596604530 endingPage "e0171453" @default.
- W2596604530 startingPage "e0171453" @default.
- W2596604530 abstract "Apolipoprotein D (ApoD) has been proposed as a predictor of breast cancer recurrence among estrogen receptor-positive (ER+), tamoxifen-treated patients.We conducted a population-based case-control study nested in a population of 11,251 women aged 35-69 years at diagnosis with Stage I-III breast cancer between 1985 and 2001 on Denmark's Jutland Peninsula and registered with the Danish Breast Cancer Cooperative Group. We identified 541 recurrent or contralateral breast cancers cases among women with ER+ disease treated with tamoxifen for at least 1 year and 300 cases in women with ER- disease never treated with tamoxifen. We matched one control subject per case and assessed ApoD expression in the tumor cell nucleus and cytoplasm using tissue microarray immunohistochemistry. We computed the odds ratio (OR) associating ApoD expression with recurrence and adjusted for potential confounding using logistic regression.Cytoplasmic ApoD expression was seen in 68% of ER+ tumors, in 66% of ER- tumors, and in 66% of controls across both groups. In women with ER+ tumors, the associations of cytoplasmic ApoD expression with recurrence (OR = 1.0; 95% CI = 0.7 to 1.4) and increasing cytoplasmic expression with recurrence (OR = 1.0; 95% CI = 0.996 to 1.003) were null, as were those for women with ER- tumors. Associations for nuclear ApoD expression and combined nuclear and cytoplasmic expression were similarly near-null.ApoD expression is likely not a predictor of recurrence in tamoxifen-treated patients.This study eliminates the previously suggested marker ApoD as a predictor of recurrence among tamoxifen-treated women." @default.
- W2596604530 created "2017-03-23" @default.
- W2596604530 creator A5001153579 @default.
- W2596604530 creator A5003110329 @default.
- W2596604530 creator A5006148147 @default.
- W2596604530 creator A5007457211 @default.
- W2596604530 creator A5034600500 @default.
- W2596604530 creator A5038894772 @default.
- W2596604530 creator A5039413618 @default.
- W2596604530 creator A5053033359 @default.
- W2596604530 creator A5058866005 @default.
- W2596604530 creator A5066076502 @default.
- W2596604530 creator A5074952556 @default.
- W2596604530 creator A5078293062 @default.
- W2596604530 creator A5079241058 @default.
- W2596604530 creator A5082359162 @default.
- W2596604530 date "2017-03-16" @default.
- W2596604530 modified "2023-10-17" @default.
- W2596604530 title "Apolipoprotein D expression does not predict breast cancer recurrence among tamoxifen-treated patients" @default.
- W2596604530 cites W1271389891 @default.
- W2596604530 cites W1437839308 @default.
- W2596604530 cites W1529944274 @default.
- W2596604530 cites W1943317637 @default.
- W2596604530 cites W1961026612 @default.
- W2596604530 cites W1970448592 @default.
- W2596604530 cites W1978670003 @default.
- W2596604530 cites W1986454158 @default.
- W2596604530 cites W2002064995 @default.
- W2596604530 cites W2004881066 @default.
- W2596604530 cites W2009123118 @default.
- W2596604530 cites W2012502745 @default.
- W2596604530 cites W2026467905 @default.
- W2596604530 cites W2028691872 @default.
- W2596604530 cites W2028724427 @default.
- W2596604530 cites W2041637660 @default.
- W2596604530 cites W2044702943 @default.
- W2596604530 cites W2061671852 @default.
- W2596604530 cites W2071406208 @default.
- W2596604530 cites W2078358657 @default.
- W2596604530 cites W2079500772 @default.
- W2596604530 cites W2089595068 @default.
- W2596604530 cites W2112780046 @default.
- W2596604530 cites W2117305280 @default.
- W2596604530 cites W2118728607 @default.
- W2596604530 cites W2134444110 @default.
- W2596604530 cites W2137942385 @default.
- W2596604530 cites W2155622098 @default.
- W2596604530 cites W2158288355 @default.
- W2596604530 cites W2167139543 @default.
- W2596604530 cites W2171583319 @default.
- W2596604530 cites W2400866294 @default.
- W2596604530 cites W2412131849 @default.
- W2596604530 cites W2415122743 @default.
- W2596604530 cites W4254547023 @default.
- W2596604530 cites W68324521 @default.
- W2596604530 doi "https://doi.org/10.1371/journal.pone.0171453" @default.
- W2596604530 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5354364" @default.
- W2596604530 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28301514" @default.
- W2596604530 hasPublicationYear "2017" @default.
- W2596604530 type Work @default.
- W2596604530 sameAs 2596604530 @default.
- W2596604530 citedByCount "6" @default.
- W2596604530 countsByYear W25966045302018 @default.
- W2596604530 countsByYear W25966045302019 @default.
- W2596604530 countsByYear W25966045302020 @default.
- W2596604530 countsByYear W25966045302021 @default.
- W2596604530 countsByYear W25966045302022 @default.
- W2596604530 crossrefType "journal-article" @default.
- W2596604530 hasAuthorship W2596604530A5001153579 @default.
- W2596604530 hasAuthorship W2596604530A5003110329 @default.
- W2596604530 hasAuthorship W2596604530A5006148147 @default.
- W2596604530 hasAuthorship W2596604530A5007457211 @default.
- W2596604530 hasAuthorship W2596604530A5034600500 @default.
- W2596604530 hasAuthorship W2596604530A5038894772 @default.
- W2596604530 hasAuthorship W2596604530A5039413618 @default.
- W2596604530 hasAuthorship W2596604530A5053033359 @default.
- W2596604530 hasAuthorship W2596604530A5058866005 @default.
- W2596604530 hasAuthorship W2596604530A5066076502 @default.
- W2596604530 hasAuthorship W2596604530A5074952556 @default.
- W2596604530 hasAuthorship W2596604530A5078293062 @default.
- W2596604530 hasAuthorship W2596604530A5079241058 @default.
- W2596604530 hasAuthorship W2596604530A5082359162 @default.
- W2596604530 hasBestOaLocation W25966045301 @default.
- W2596604530 hasConcept C121608353 @default.
- W2596604530 hasConcept C126322002 @default.
- W2596604530 hasConcept C142724271 @default.
- W2596604530 hasConcept C143998085 @default.
- W2596604530 hasConcept C193270364 @default.
- W2596604530 hasConcept C204232928 @default.
- W2596604530 hasConcept C2777176818 @default.
- W2596604530 hasConcept C2908647359 @default.
- W2596604530 hasConcept C530470458 @default.
- W2596604530 hasConcept C71924100 @default.
- W2596604530 hasConcept C84606932 @default.
- W2596604530 hasConcept C99454951 @default.
- W2596604530 hasConceptScore W2596604530C121608353 @default.
- W2596604530 hasConceptScore W2596604530C126322002 @default.
- W2596604530 hasConceptScore W2596604530C142724271 @default.