Matches in SemOpenAlex for { <https://semopenalex.org/work/W2596662456> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2596662456 abstract "Planaria are soft-bodied, bilateral flatworms of the phylum Playhelminthes. They are covered in cilia and use ciliary-gliding to traverse the substratum while hunting. Their body surface is covered in a layer of viscous slime primarily derived from specialised secretory granules known as rhabdites. The slime must somehow stay associated with the surface of the animal in aqueous environments whilst also lubricating the interface of the animal and the surfaces over which the animal moves. The slime prevents damage to the animal's soft body and also contributes to adhesion to the substratum. In order to gain insight into how it might achieve these diverse functions, we performed electron microscopic examination of the slime's structure. Analysis of two freshwater flatworms from the UK Schmidtea polychroa (Schmidt, 1861) and Polycelis tenuis (Ijima, 1884) revealed a high level of organisation of the slime layer and a variety of ejected slime structures. We show that these structures are rich in sulphated glycosaminoglycans (sGAGs). Most of these (269 of 285 examined) appear to be topologically-closed spheroids that we name ball-GAGs. Another class appears to burst to release flower- and star-like clusters which adhere to motile cilia. We also observe fibrous nets that are associated with entrapped bacteria. Examination of the structure of rhabdites ejected onto a porous surface suggests a mechanism by which their structure allows them to both bind to the porous surface and provide a smooth layer over which the animal could glide. Such sGAG-based structures might provide models for the design of artificial biomimetic replacements for tears, saliva, bio-compatible lubricants or drug-delivery vehicles." @default.
- W2596662456 created "2017-03-23" @default.
- W2596662456 creator A5028997721 @default.
- W2596662456 date "2017-01-01" @default.
- W2596662456 modified "2023-10-04" @default.
- W2596662456 title "Sulphated glycosaminoglycans support an assortment of planarian rhabdite structures" @default.
- W2596662456 cites W1510471268 @default.
- W2596662456 cites W1964186648 @default.
- W2596662456 cites W1969373623 @default.
- W2596662456 cites W1983912504 @default.
- W2596662456 cites W1984243079 @default.
- W2596662456 cites W1985024253 @default.
- W2596662456 cites W2004539400 @default.
- W2596662456 cites W2019959134 @default.
- W2596662456 cites W2041615431 @default.
- W2596662456 cites W2099797283 @default.
- W2596662456 cites W2115831638 @default.
- W2596662456 cites W2151142378 @default.
- W2596662456 cites W2167990668 @default.
- W2596662456 cites W2176499553 @default.
- W2596662456 cites W2326773736 @default.
- W2596662456 cites W2330395390 @default.
- W2596662456 cites W2399550214 @default.
- W2596662456 cites W2572542501 @default.
- W2596662456 cites W2796009261 @default.
- W2596662456 cites W28805563 @default.
- W2596662456 doi "https://doi.org/10.1242/bio.024554" @default.
- W2596662456 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5450325" @default.
- W2596662456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28302668" @default.
- W2596662456 hasPublicationYear "2017" @default.
- W2596662456 type Work @default.
- W2596662456 sameAs 2596662456 @default.
- W2596662456 citedByCount "5" @default.
- W2596662456 countsByYear W25966624562018 @default.
- W2596662456 countsByYear W25966624562019 @default.
- W2596662456 countsByYear W25966624562023 @default.
- W2596662456 crossrefType "journal-article" @default.
- W2596662456 hasAuthorship W2596662456A5028997721 @default.
- W2596662456 hasBestOaLocation W25966624561 @default.
- W2596662456 hasConcept C100094513 @default.
- W2596662456 hasConcept C105702510 @default.
- W2596662456 hasConcept C153074725 @default.
- W2596662456 hasConcept C171056886 @default.
- W2596662456 hasConcept C2524010 @default.
- W2596662456 hasConcept C2775935104 @default.
- W2596662456 hasConcept C2777113906 @default.
- W2596662456 hasConcept C2910722709 @default.
- W2596662456 hasConcept C3020541326 @default.
- W2596662456 hasConcept C33923547 @default.
- W2596662456 hasConcept C86803240 @default.
- W2596662456 hasConcept C95444343 @default.
- W2596662456 hasConceptScore W2596662456C100094513 @default.
- W2596662456 hasConceptScore W2596662456C105702510 @default.
- W2596662456 hasConceptScore W2596662456C153074725 @default.
- W2596662456 hasConceptScore W2596662456C171056886 @default.
- W2596662456 hasConceptScore W2596662456C2524010 @default.
- W2596662456 hasConceptScore W2596662456C2775935104 @default.
- W2596662456 hasConceptScore W2596662456C2777113906 @default.
- W2596662456 hasConceptScore W2596662456C2910722709 @default.
- W2596662456 hasConceptScore W2596662456C3020541326 @default.
- W2596662456 hasConceptScore W2596662456C33923547 @default.
- W2596662456 hasConceptScore W2596662456C86803240 @default.
- W2596662456 hasConceptScore W2596662456C95444343 @default.
- W2596662456 hasLocation W25966624561 @default.
- W2596662456 hasLocation W25966624562 @default.
- W2596662456 hasLocation W25966624563 @default.
- W2596662456 hasLocation W25966624564 @default.
- W2596662456 hasLocation W25966624565 @default.
- W2596662456 hasLocation W25966624566 @default.
- W2596662456 hasLocation W25966624567 @default.
- W2596662456 hasLocation W25966624568 @default.
- W2596662456 hasOpenAccess W2596662456 @default.
- W2596662456 hasPrimaryLocation W25966624561 @default.
- W2596662456 hasRelatedWork W1927064723 @default.
- W2596662456 hasRelatedWork W2106974809 @default.
- W2596662456 hasRelatedWork W2108216230 @default.
- W2596662456 hasRelatedWork W2140295200 @default.
- W2596662456 hasRelatedWork W2149163258 @default.
- W2596662456 hasRelatedWork W2298340958 @default.
- W2596662456 hasRelatedWork W2511115540 @default.
- W2596662456 hasRelatedWork W2596662456 @default.
- W2596662456 hasRelatedWork W283333993 @default.
- W2596662456 hasRelatedWork W2947300110 @default.
- W2596662456 isParatext "false" @default.
- W2596662456 isRetracted "false" @default.
- W2596662456 magId "2596662456" @default.
- W2596662456 workType "article" @default.