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• W2596770143 endingPage "1194" @default.
• W2596770143 startingPage "1183" @default.
• W2596770143 abstract "The intestinal epithelium forms a key protective barrier that separates internal organs from the harmful environment of the gut lumen. Increased permeability of the gut barrier is a common manifestation of different inflammatory disorders contributing to the severity of disease. Barrier permeability is controlled by epithelial adherens junctions and tight junctions. Junctional assembly and integrity depend on fundamental homeostatic processes such as cell differentiation, rearrangements of the cytoskeleton, and vesicle trafficking. Alterations of intestinal epithelial homeostasis during mucosal inflammation may impair structure and remodeling of apical junctions, resulting in increased permeability of the gut barrier. In this review, we summarize recent advances in our understanding of how altered epithelial homeostasis affects the structure and function of adherens junctions and tight junctions in the inflamed gut. Specifically, we focus on the transcription reprogramming of the cell, alterations in the actin cytoskeleton, and junctional endocytosis and exocytosis. We pay special attention to knockout mouse model studies and discuss the relevance of these mechanisms to human gastrointestinal disorders." @default.
• W2596770143 created "2017-03-23" @default.
• W2596770143 creator A5040857890 @default.
• W2596770143 creator A5042846824 @default.
• W2596770143 date "2017-07-01" @default.
• W2596770143 modified "2023-10-16" @default.
• W2596770143 title "Disruption of the epithelial barrier during intestinal inflammation: Quest for new molecules and mechanisms" @default.
• W2596770143 cites W148077135 @default.
• W2596770143 cites W1512533030 @default.
• W2596770143 cites W1525528026 @default.
• W2596770143 cites W1697129306 @default.
• W2596770143 cites W1810908282 @default.
• W2596770143 cites W191402491 @default.
• W2596770143 cites W191916476 @default.
• W2596770143 cites W1927073913 @default.
• W2596770143 cites W1971896370 @default.
• W2596770143 cites W1973053074 @default.
• W2596770143 cites W1973262419 @default.
• W2596770143 cites W1973541175 @default.
• W2596770143 cites W1974972022 @default.
• W2596770143 cites W1977683874 @default.
• W2596770143 cites W1977699070 @default.
• W2596770143 cites W1978651800 @default.
• W2596770143 cites W1982205229 @default.
• W2596770143 cites W1985312853 @default.
• W2596770143 cites W1986159120 @default.
• W2596770143 cites W1986532926 @default.
• W2596770143 cites W1987282988 @default.
• W2596770143 cites W1988404061 @default.
• W2596770143 cites W1991836246 @default.
• W2596770143 cites W1995640884 @default.
• W2596770143 cites W1995754670 @default.
• W2596770143 cites W1999750427 @default.
• W2596770143 cites W2002167899 @default.
• W2596770143 cites W2002461953 @default.
• W2596770143 cites W2003591869 @default.
• W2596770143 cites W2004723568 @default.
• W2596770143 cites W2006449957 @default.
• W2596770143 cites W2008039606 @default.
• W2596770143 cites W2010580393 @default.
• W2596770143 cites W2013197667 @default.
• W2596770143 cites W2015174250 @default.
• W2596770143 cites W2019154269 @default.
• W2596770143 cites W2020444219 @default.
• W2596770143 cites W2021944416 @default.
• W2596770143 cites W2022364566 @default.
• W2596770143 cites W2024979614 @default.
• W2596770143 cites W2025819729 @default.
• W2596770143 cites W2026240985 @default.
• W2596770143 cites W2026700628 @default.
• W2596770143 cites W2027586189 @default.
• W2596770143 cites W2028224423 @default.
• W2596770143 cites W2030029307 @default.
• W2596770143 cites W2032380005 @default.
• W2596770143 cites W2032781792 @default.
• W2596770143 cites W2032930150 @default.
• W2596770143 cites W2036221207 @default.
• W2596770143 cites W2036281609 @default.
• W2596770143 cites W2048691571 @default.
• W2596770143 cites W2049269681 @default.
• W2596770143 cites W2056700437 @default.
• W2596770143 cites W2057918252 @default.
• W2596770143 cites W2060028405 @default.
• W2596770143 cites W2060379087 @default.
• W2596770143 cites W2063875318 @default.
• W2596770143 cites W2064390634 @default.
• W2596770143 cites W2064964362 @default.
• W2596770143 cites W2067350995 @default.
• W2596770143 cites W2071035219 @default.
• W2596770143 cites W2071683944 @default.
• W2596770143 cites W2072267994 @default.
• W2596770143 cites W2073366060 @default.
• W2596770143 cites W2073406173 @default.
• W2596770143 cites W2075487594 @default.
• W2596770143 cites W2076998894 @default.
• W2596770143 cites W2081165530 @default.
• W2596770143 cites W2081599491 @default.
• W2596770143 cites W2085966326 @default.
• W2596770143 cites W2088892772 @default.
• W2596770143 cites W2090919838 @default.
• W2596770143 cites W2092582603 @default.
• W2596770143 cites W2093861982 @default.
• W2596770143 cites W2094076302 @default.
• W2596770143 cites W2096460816 @default.
• W2596770143 cites W2097352622 @default.
• W2596770143 cites W2098520903 @default.
• W2596770143 cites W2100093202 @default.
• W2596770143 cites W2101203073 @default.
• W2596770143 cites W2101976554 @default.
• W2596770143 cites W2103033566 @default.
• W2596770143 cites W2103137874 @default.
• W2596770143 cites W2103536507 @default.
• W2596770143 cites W2107903378 @default.
• W2596770143 cites W2108875521 @default.
• W2596770143 cites W2108963851 @default.
• W2596770143 cites W2110251267 @default.
• W2596770143 cites W2113971980 @default.
• W2596770143 cites W2116946576 @default.

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