FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2596804938> ?p ?o ?g. }

• W2596804938 abstract "ABSTRACT Extended-spectrum β-lactamases (ESBLs) and plasmid-mediated AmpC β-lactamases (pAmpC) are enzymes able to hydrolyze a large variety of β-lactam antibiotics, including third-generation cephalosporins and monobactams. Broilers and broiler meat products can be highly contaminated with ESBL- and pAmpC-producing Escherichia coli strains, also known as extended-spectrum cephalosporin (ESC)-resistant E. coli strains, and can be a source for human infections. As few data on interventions to reduce the presence of ESC-resistant E. coli in broilers are available, we used transmission experiments to examine the role of competitive exclusion (CE) on reducing transmission and excretion in broilers. A broiler model to study the transmission of ESC-resistant E. coli was set up. Day-old chickens were challenged with an ESBL-producing E. coli strain isolated from healthy broilers in the Netherlands. Challenged and not challenged chicks were housed together in pairs or in groups, and ESBL-producing E. coli transmission was monitored via selective culturing of cloacal swab specimens. We observed a statistically significant reduction in both the transmission and excretion of ESBL-producing E. coli in chicks treated with the probiotic flora before E. coli challenge compared to the transmission and excretion in untreated controls. In conclusion, our results support the use of competitive exclusion as an intervention strategy to control ESC-resistant E. coli in the field. IMPORTANCE Extended-spectrum β-lactamases (ESBLs) and plasmid-mediated AmpC β-lactamases are a primary cause of resistance to β-lactam antibiotics among members of the family Enterobacteriaceae in humans, animals, and the environment. Food-producing animals are not exempt from this, with a high prevalence being seen in broilers, and there is evidence pointing to a possible foodborne source for human contamination. We investigated the effect of administration of a commercial probiotic product as an intervention to reduce the amount of ESBL-producing Escherichia coli in broilers. Our results showed a substantial reduction in the level of colonization of broiler intestines by ESBL-producing E. coli after administration of commercial probiotic product. The protective effect provided by these probiotics could be implemented on a larger scale in poultry production. Reductions in the levels of ESBL-producing Enterobacteriaceae in the food chain would considerably benefit public health." @default.
• W2596804938 created "2017-03-23" @default.
• W2596804938 creator A5008847384 @default.
• W2596804938 creator A5021426567 @default.
• W2596804938 creator A5033483720 @default.
• W2596804938 creator A5036061329 @default.
• W2596804938 creator A5039590975 @default.
• W2596804938 creator A5043979509 @default.
• W2596804938 creator A5089094686 @default.
• W2596804938 creator A5091170353 @default.
• W2596804938 date "2017-06-01" @default.
• W2596804938 modified "2023-10-01" @default.
• W2596804938 title "Competitive Exclusion Reduces Transmission and Excretion of Extended-Spectrum-β-Lactamase-Producing Escherichia coli in Broilers" @default.
• W2596804938 cites W1496672667 @default.
• W2596804938 cites W1604422273 @default.
• W2596804938 cites W1767512920 @default.
• W2596804938 cites W1977951217 @default.
• W2596804938 cites W1987635163 @default.
• W2596804938 cites W2010893344 @default.
• W2596804938 cites W2016363064 @default.
• W2596804938 cites W2017133488 @default.
• W2596804938 cites W2018819380 @default.
• W2596804938 cites W2022229870 @default.
• W2596804938 cites W2031160325 @default.
• W2596804938 cites W2031965136 @default.
• W2596804938 cites W2039850897 @default.
• W2596804938 cites W2042020968 @default.
• W2596804938 cites W2058415702 @default.
• W2596804938 cites W2059291212 @default.
• W2596804938 cites W2070144101 @default.
• W2596804938 cites W2077345258 @default.
• W2596804938 cites W2080778435 @default.
• W2596804938 cites W2083847905 @default.
• W2596804938 cites W2084338441 @default.
• W2596804938 cites W2087724386 @default.
• W2596804938 cites W2094873300 @default.
• W2596804938 cites W2099176808 @default.
• W2596804938 cites W2099303284 @default.
• W2596804938 cites W2100971121 @default.
• W2596804938 cites W2101689783 @default.
• W2596804938 cites W2112385154 @default.
• W2596804938 cites W2113532719 @default.
• W2596804938 cites W2116199264 @default.
• W2596804938 cites W2126341187 @default.
• W2596804938 cites W2130706154 @default.
• W2596804938 cites W2136776347 @default.
• W2596804938 cites W2144943888 @default.
• W2596804938 cites W2145404099 @default.
• W2596804938 cites W2151295927 @default.
• W2596804938 cites W2161064937 @default.
• W2596804938 cites W2164030271 @default.
• W2596804938 cites W2169550448 @default.
• W2596804938 cites W2169701189 @default.
• W2596804938 cites W2175838456 @default.
• W2596804938 cites W2292024711 @default.
• W2596804938 cites W2472892211 @default.
• W2596804938 cites W2518643713 @default.
• W2596804938 doi "https://doi.org/10.1128/aem.03439-16" @default.
• W2596804938 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5440715" @default.
• W2596804938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28314728" @default.
• W2596804938 hasPublicationYear "2017" @default.
• W2596804938 type Work @default.
• W2596804938 sameAs 2596804938 @default.
• W2596804938 citedByCount "41" @default.
• W2596804938 countsByYear W25968049382018 @default.
• W2596804938 countsByYear W25968049382019 @default.
• W2596804938 countsByYear W25968049382020 @default.
• W2596804938 countsByYear W25968049382021 @default.
• W2596804938 countsByYear W25968049382022 @default.
• W2596804938 countsByYear W25968049382023 @default.
• W2596804938 crossrefType "journal-article" @default.
• W2596804938 hasAuthorship W2596804938A5008847384 @default.
• W2596804938 hasAuthorship W2596804938A5021426567 @default.
• W2596804938 hasAuthorship W2596804938A5033483720 @default.
• W2596804938 hasAuthorship W2596804938A5036061329 @default.
• W2596804938 hasAuthorship W2596804938A5039590975 @default.
• W2596804938 hasAuthorship W2596804938A5043979509 @default.
• W2596804938 hasAuthorship W2596804938A5089094686 @default.
• W2596804938 hasAuthorship W2596804938A5091170353 @default.
• W2596804938 hasBestOaLocation W25968049381 @default.
• W2596804938 hasConcept C10146269 @default.
• W2596804938 hasConcept C104317684 @default.
• W2596804938 hasConcept C119599485 @default.
• W2596804938 hasConcept C127413603 @default.
• W2596804938 hasConcept C22744801 @default.
• W2596804938 hasConcept C2776021129 @default.
• W2596804938 hasConcept C2778910516 @default.
• W2596804938 hasConcept C2780289900 @default.
• W2596804938 hasConcept C31903555 @default.
• W2596804938 hasConcept C501593827 @default.
• W2596804938 hasConcept C547475151 @default.
• W2596804938 hasConcept C552990157 @default.
• W2596804938 hasConcept C55493867 @default.
• W2596804938 hasConcept C64778159 @default.
• W2596804938 hasConcept C761482 @default.
• W2596804938 hasConcept C86803240 @default.
• W2596804938 hasConcept C89423630 @default.
• W2596804938 hasConcept C94665300 @default.
• W2596804938 hasConceptScore W2596804938C10146269 @default.
• W2596804938 hasConceptScore W2596804938C104317684 @default.

• next