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- W2596834247 abstract "Kinetics of bony ingrowth to control and heat-treated TI-6AI-4v screw implants and pure titanium mesh implants inserted into the medullary canal of the femur in rats was followed by mechanic and biochemical methods. A progressive and significant increase in the bony ingrowth to the implants as reflected by their interfacial shear strengths in the femur was observed with time. These values were negligible at the time of insertion and exceeded 2.13 MPa at 35 days post surgery for control Ti-6AI-4v implants. The specific activity of alkaline phosphatase in tissue extracts around the screw implant showed a peak at six days postoperatively. At all time intervals following surgery the shear strengths of the heat-treated Ti-6Al-4v screw implants and pure titanium mesh cylinders were 2 to 5.5 fold significantly higher than the control untreated implants. It is concluded that the heat treatment which most probably modifies the surface chemical properties of the implants, significantly affects the process of differentiation of osteoblasts from osteoprogenitor cells in the marrow or the rate of bone deposition next to the implants. The results of the present study are of direct clinical relevance in improving the function of cementless artificial joints and dental implants." @default.
- W2596834247 created "2017-03-23" @default.
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- W2596834247 date "1991-01-01" @default.
- W2596834247 modified "2023-09-27" @default.
- W2596834247 title "ENHANcmmNT OF BONY INGROWI'H 'l'O 'I 'fANIUM AND TITANIUM ALLOY ORTHOPAEDIC IMPLANTS IN EXPEllliaJl'.NTAL MODEL IN TIlE RAT" @default.
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