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- W2597003850 abstract "Abstract Photoinduced single electron transfer (SET) cyclization processes for synthesis of a Sansalvamide A analog containing double pharmacophores (cyclicpeptides and O-phthalimide moiety) is described to develop novel antitumor cyclopeptide drug. The resultant compound is active in drug-sensitive HeLa, HepG-2 and MCF-7 cell lines. Specifically, the title compound was found to inhibit MCF-7 cells with an IC 50 value of 15 μM (13.4 μg/mL), which may serve as a potential candidate for antitumor drug development." @default.
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- W2597003850 date "2017-04-01" @default.
- W2597003850 modified "2023-09-24" @default.
- W2597003850 title "Photo-induced synthesis and in vitro biological activity of a Sansalvamide A analog" @default.
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- W2597003850 doi "https://doi.org/10.1016/j.tetlet.2017.03.042" @default.
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