FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2597050157> ?p ?o ?g. }

• W2597050157 endingPage "91" @default.
• W2597050157 startingPage "79" @default.
• W2597050157 abstract "Perivascular adipose tissue (PVAT), which reduces vascular contractility, is dysfunctional in the male offspring of rats fed a high-fat diet (HFD), partially due to a reduced NO bioavailability. O-GlcNAcylation of eNOS decreases its activity, thus we investigated the role of O-GlcNAcylation in the prenatal programming of PVAT dysfunction. Female Sprague-Dawley rats were fed either a control (10% fat) or an obesogenic HFD (45% fat) diet for 12 weeks prior to mating, and throughout pregnancy and lactation. Offspring were weaned onto the control diet and were killed at 12 and 24 weeks of age. Mesenteric arteries from the 12-week-old offspring of HFD dams (HFDO) contracted less to U46619; these effects were mimicked by glucosamine in control arteries. PVAT from 12- and 24-week-old controls, but not from HFDO, exerted an anticontractile effect. Glucosamine attenuated the anticontractile effect of PVAT in the vessels from controls but not from HFDO. AMP-activated protein kinase (AMPK) activation (with A769662) partially restored an anticontractile effect in glucosamine-treated controls and HFDO PVAT. Glucosamine decreased AMPK activity and expression in HFDO PVAT, although phosphorylated eNOS expression was only reduced in that from males. The loss of anticontractile effect of HFDO PVAT is likely to result from increased O-GlcNAcylation, which decreased AMPK activity and, in males, decreased NO bioavailability." @default.
• W2597050157 created "2017-03-23" @default.
• W2597050157 creator A5003792853 @default.
• W2597050157 creator A5056967745 @default.
• W2597050157 creator A5087102130 @default.
• W2597050157 creator A5088584936 @default.
• W2597050157 date "2017-01-01" @default.
• W2597050157 modified "2023-10-14" @default.
• W2597050157 title "The Role of O-GlcNAcylation in Perivascular Adipose Tissue Dysfunction of Offspring of High-Fat Diet-Fed Rats" @default.
• W2597050157 cites W1511269911 @default.
• W2597050157 cites W1561322846 @default.
• W2597050157 cites W191754116 @default.
• W2597050157 cites W1968813770 @default.
• W2597050157 cites W1970445852 @default.
• W2597050157 cites W1981809260 @default.
• W2597050157 cites W1982159046 @default.
• W2597050157 cites W1983591854 @default.
• W2597050157 cites W1989560248 @default.
• W2597050157 cites W2004192807 @default.
• W2597050157 cites W2004619700 @default.
• W2597050157 cites W2009705987 @default.
• W2597050157 cites W2010413021 @default.
• W2597050157 cites W2012775549 @default.
• W2597050157 cites W2017558222 @default.
• W2597050157 cites W2020782232 @default.
• W2597050157 cites W2030328205 @default.
• W2597050157 cites W2038482691 @default.
• W2597050157 cites W2043916567 @default.
• W2597050157 cites W2043944896 @default.
• W2597050157 cites W2044437167 @default.
• W2597050157 cites W2052860092 @default.
• W2597050157 cites W2054879972 @default.
• W2597050157 cites W2055029805 @default.
• W2597050157 cites W2057218469 @default.
• W2597050157 cites W2061444003 @default.
• W2597050157 cites W2067474104 @default.
• W2597050157 cites W2067743393 @default.
• W2597050157 cites W2068820862 @default.
• W2597050157 cites W2072165896 @default.
• W2597050157 cites W2081254560 @default.
• W2597050157 cites W2083321610 @default.
• W2597050157 cites W2087136121 @default.
• W2597050157 cites W2087279229 @default.
• W2597050157 cites W2087839573 @default.
• W2597050157 cites W2091932914 @default.
• W2597050157 cites W2098696702 @default.
• W2597050157 cites W2120036668 @default.
• W2597050157 cites W2121804122 @default.
• W2597050157 cites W2127295385 @default.
• W2597050157 cites W2135086300 @default.
• W2597050157 cites W2137199359 @default.
• W2597050157 cites W2150377102 @default.
• W2597050157 cites W2152809661 @default.
• W2597050157 cites W2158365429 @default.
• W2597050157 cites W2160101394 @default.
• W2597050157 cites W2165139442 @default.
• W2597050157 cites W2279441901 @default.
• W2597050157 cites W2338334739 @default.
• W2597050157 doi "https://doi.org/10.1159/000458422" @default.
• W2597050157 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5569708" @default.
• W2597050157 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28376507" @default.
• W2597050157 hasPublicationYear "2017" @default.
• W2597050157 type Work @default.
• W2597050157 sameAs 2597050157 @default.
• W2597050157 citedByCount "6" @default.
• W2597050157 countsByYear W25970501572018 @default.
• W2597050157 countsByYear W25970501572020 @default.
• W2597050157 crossrefType "journal-article" @default.
• W2597050157 hasAuthorship W2597050157A5003792853 @default.
• W2597050157 hasAuthorship W2597050157A5056967745 @default.
• W2597050157 hasAuthorship W2597050157A5087102130 @default.
• W2597050157 hasAuthorship W2597050157A5088584936 @default.
• W2597050157 hasBestOaLocation W25970501571 @default.
• W2597050157 hasConcept C112672928 @default.
• W2597050157 hasConcept C126322002 @default.
• W2597050157 hasConcept C134018914 @default.
• W2597050157 hasConcept C171089720 @default.
• W2597050157 hasConcept C184235292 @default.
• W2597050157 hasConcept C2776659692 @default.
• W2597050157 hasConcept C2776820930 @default.
• W2597050157 hasConcept C2777622882 @default.
• W2597050157 hasConcept C2778326061 @default.
• W2597050157 hasConcept C2779234561 @default.
• W2597050157 hasConcept C2780124434 @default.
• W2597050157 hasConcept C2780771799 @default.
• W2597050157 hasConcept C519581460 @default.
• W2597050157 hasConcept C54355233 @default.
• W2597050157 hasConcept C71924100 @default.
• W2597050157 hasConcept C86803240 @default.
• W2597050157 hasConcept C95444343 @default.
• W2597050157 hasConcept C97029542 @default.
• W2597050157 hasConceptScore W2597050157C112672928 @default.
• W2597050157 hasConceptScore W2597050157C126322002 @default.
• W2597050157 hasConceptScore W2597050157C134018914 @default.
• W2597050157 hasConceptScore W2597050157C171089720 @default.
• W2597050157 hasConceptScore W2597050157C184235292 @default.
• W2597050157 hasConceptScore W2597050157C2776659692 @default.
• W2597050157 hasConceptScore W2597050157C2776820930 @default.

• next