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• W2597057763 abstract "Variation in an animal's spatial environment can induce variation in the hippocampus, an area of the brain involved in spatial cognitive processing. Specifically, increased spatial area use is correlated with increased hippocampal attributes, such as volume and neurogenesis. In the side-blotched lizard (Uta stansburiana), males demonstrate alternative reproductive tactics and are either territorial-defending large, clearly defined spatial boundaries-or non-territorial-traversing home ranges that are smaller than the territorial males' territories. Our previous work demonstrated cortical volume (reptilian hippocampal homolog) correlates with these spatial niches. We found that territorial holders have larger medial cortices than non-territory holders, yet these differences in the neural architecture demonstrated some degree of plasticity as well. Although we have demonstrated a link among territoriality, spatial use, and brain plasticity, the mechanisms that underlie this relationship are unclear. Previous studies found that higher testosterone levels can induce increased use of the spatial area and can cause an upregulation in hippocampal attributes. Thus, testosterone may be the mechanistic link between spatial area use and the brain. What remains unclear, however, is if testosterone can affect the cortices independent of spatial experiences and whether testosterone differentially interacts with territorial status to produce the resultant cortical phenotype. In this study, we compared neurogenesis as measured by the total number of doublecortin-positive cells and cortical volume between territorial and non-territorial males supplemented with testosterone. We found no significant differences in the number of doublecortin-positive cells or cortical volume among control territorial, control non-territorial, and testosterone-supplemented non-territorial males, while testosterone-supplemented territorial males had smaller medial cortices containing fewer doublecortin-positive cells. These results demonstrate that testosterone can modulate medial cortical attributes outside of differential spatial processing experiences but that territorial males appear to be more sensitive to alterations in testosterone levels compared with non-territorial males." @default.
• W2597057763 created "2017-03-23" @default.
• W2597057763 creator A5011655281 @default.
• W2597057763 creator A5023407555 @default.
• W2597057763 creator A5062433915 @default.
• W2597057763 creator A5069722227 @default.
• W2597057763 creator A5077647440 @default.
• W2597057763 date "2017-03-01" @default.
• W2597057763 modified "2023-10-13" @default.
• W2597057763 title "Increased Testosterone Decreases Medial Cortical Volume and Neurogenesis in Territorial Side-Blotched Lizards (Uta stansburiana)" @default.
• W2597057763 cites W137027176 @default.
• W2597057763 cites W1557156999 @default.
• W2597057763 cites W1570054828 @default.
• W2597057763 cites W1607341300 @default.
• W2597057763 cites W1774664525 @default.
• W2597057763 cites W1775250759 @default.
• W2597057763 cites W1848517268 @default.
• W2597057763 cites W1891847621 @default.
• W2597057763 cites W1900947733 @default.
• W2597057763 cites W1953707781 @default.
• W2597057763 cites W1973722262 @default.
• W2597057763 cites W1977896547 @default.
• W2597057763 cites W1982695962 @default.
• W2597057763 cites W1982830349 @default.
• W2597057763 cites W1984325684 @default.
• W2597057763 cites W1986346910 @default.
• W2597057763 cites W1986435905 @default.
• W2597057763 cites W1986662149 @default.
• W2597057763 cites W1987848336 @default.
• W2597057763 cites W1989420060 @default.
• W2597057763 cites W1990765405 @default.
• W2597057763 cites W1992157464 @default.
• W2597057763 cites W1992524801 @default.
• W2597057763 cites W1995175293 @default.
• W2597057763 cites W1995638809 @default.
• W2597057763 cites W1996322761 @default.
• W2597057763 cites W1997426379 @default.
• W2597057763 cites W1998072745 @default.
• W2597057763 cites W2001488495 @default.
• W2597057763 cites W2002661290 @default.
• W2597057763 cites W2003426180 @default.
• W2597057763 cites W2005324727 @default.
• W2597057763 cites W2008412245 @default.
• W2597057763 cites W2008744929 @default.
• W2597057763 cites W2008758661 @default.
• W2597057763 cites W2010395737 @default.
• W2597057763 cites W2011656967 @default.
• W2597057763 cites W2012500075 @default.
• W2597057763 cites W2014381930 @default.
• W2597057763 cites W2016450991 @default.
• W2597057763 cites W2017360403 @default.
• W2597057763 cites W2018266532 @default.
• W2597057763 cites W2018765209 @default.
• W2597057763 cites W2020588628 @default.
• W2597057763 cites W2022705820 @default.
• W2597057763 cites W2023500766 @default.
• W2597057763 cites W2025798216 @default.
• W2597057763 cites W2026812475 @default.
• W2597057763 cites W2026890508 @default.
• W2597057763 cites W2027844811 @default.
• W2597057763 cites W2028190458 @default.
• W2597057763 cites W2033535079 @default.
• W2597057763 cites W2034280301 @default.
• W2597057763 cites W2037465462 @default.
• W2597057763 cites W2037564922 @default.
• W2597057763 cites W2038202625 @default.
• W2597057763 cites W2040333141 @default.
• W2597057763 cites W2042949427 @default.
• W2597057763 cites W2044348137 @default.
• W2597057763 cites W2048210600 @default.
• W2597057763 cites W2050581082 @default.
• W2597057763 cites W2051893822 @default.
• W2597057763 cites W2055709042 @default.
• W2597057763 cites W2057189487 @default.
• W2597057763 cites W2058390748 @default.
• W2597057763 cites W2060216174 @default.
• W2597057763 cites W2060511024 @default.
• W2597057763 cites W2061019112 @default.
• W2597057763 cites W2061228762 @default.
• W2597057763 cites W2064578241 @default.
• W2597057763 cites W2065304089 @default.
• W2597057763 cites W2069384499 @default.
• W2597057763 cites W2069675394 @default.
• W2597057763 cites W2069934103 @default.
• W2597057763 cites W2071464111 @default.
• W2597057763 cites W2071807983 @default.
• W2597057763 cites W2072129731 @default.
• W2597057763 cites W2074115509 @default.
• W2597057763 cites W2078798028 @default.
• W2597057763 cites W2078936890 @default.
• W2597057763 cites W2081074747 @default.
• W2597057763 cites W2081489023 @default.
• W2597057763 cites W2081698129 @default.
• W2597057763 cites W2082057516 @default.
• W2597057763 cites W2085410500 @default.
• W2597057763 cites W2086355906 @default.
• W2597057763 cites W2086720877 @default.
• W2597057763 cites W2087483567 @default.
• W2597057763 cites W2087874336 @default.
• W2597057763 cites W2088631761 @default.

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