Matches in SemOpenAlex for { <https://semopenalex.org/work/W2597156919> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2597156919 endingPage "5039" @default.
- W2597156919 startingPage "5039" @default.
- W2597156919 abstract "5039 Background: To determine the prognosis of women with IIIC-IV endometrioid uterine cancer based on the number lymph nodes with metastatic disease Methods: Demographic and clinico-pathologic information were obtained from the Surveillance, Epidemiology and End Results Program from 1988–2001 and analyzed using Kaplan-Meier methods and Cox proportional hazards regression. Results: Of the 1,222 women diagnosed with stage IIIC-IV endometrioid uterine cancer with nodal disease, the median age was 64 (range: 28–93). All patients underwent surgical staging including a lymph node assessment and were found to have nodal metastases. 639 (52.3%) had stage IIIC, 24 (2.0%) IVA, and 559 (45.7%) IVB disease. The study cohort was divided in three subgroups based on the number of positive nodal metastases: 1, 2–5, and >5. The 5-year overall disease-specific survivals of women with 1, 2–5, and >5 positive nodes were 68.1%, 55.1% and 46.4%, respectively (p < 0.0001). The increasing number of positive nodes was associated with a worsening survival in stage IIIC (77.1%, 60.9%, 69.1%; p = 0.003) and stage IV (50.9%, 49.8%, 38.9%; p = 0.09) diseases. It appears that the extent of benign nodal resection attenuates the increase in the mortality associated with a higher number of positive nodes (see table ). Women with higher number of positive nodes received significantly less adjuvant radiotherapy at 76.8%, 59.5%, and 56.7% respectively. On multivariate analysis, age, stage, grade, number of positive lymph nodes and extent of lymph node resection were significant independent prognostic factors for survival. However, adjuvant radiation was not an important independent prognostic factor in multivariate analysis. Conclusion: Women with node positive endometrioid uterine cancers have a decreased survival associated with increasing number of positive nodes. Our data suggests that the extent of lymph node resection improves the survival of patients with node-positive uterine cancer. [Table: see text] No significant financial relationships to disclose." @default.
- W2597156919 created "2017-03-23" @default.
- W2597156919 creator A5001149399 @default.
- W2597156919 creator A5006241520 @default.
- W2597156919 creator A5024129361 @default.
- W2597156919 creator A5031844208 @default.
- W2597156919 creator A5037671271 @default.
- W2597156919 creator A5060906081 @default.
- W2597156919 creator A5091007177 @default.
- W2597156919 date "2006-06-20" @default.
- W2597156919 modified "2023-09-25" @default.
- W2597156919 title "The number of lymph nodes with metastatic disease portends for a poorer prognosis in women with stage IIIC-IV endometrioid uterine cancer" @default.
- W2597156919 doi "https://doi.org/10.1200/jco.2006.24.18_suppl.5039" @default.
- W2597156919 hasPublicationYear "2006" @default.
- W2597156919 type Work @default.
- W2597156919 sameAs 2597156919 @default.
- W2597156919 citedByCount "0" @default.
- W2597156919 crossrefType "journal-article" @default.
- W2597156919 hasAuthorship W2597156919A5001149399 @default.
- W2597156919 hasAuthorship W2597156919A5006241520 @default.
- W2597156919 hasAuthorship W2597156919A5024129361 @default.
- W2597156919 hasAuthorship W2597156919A5031844208 @default.
- W2597156919 hasAuthorship W2597156919A5037671271 @default.
- W2597156919 hasAuthorship W2597156919A5060906081 @default.
- W2597156919 hasAuthorship W2597156919A5091007177 @default.
- W2597156919 hasConcept C121608353 @default.
- W2597156919 hasConcept C126322002 @default.
- W2597156919 hasConcept C142724271 @default.
- W2597156919 hasConcept C143998085 @default.
- W2597156919 hasConcept C146357865 @default.
- W2597156919 hasConcept C151730666 @default.
- W2597156919 hasConcept C2779720271 @default.
- W2597156919 hasConcept C2780849966 @default.
- W2597156919 hasConcept C29456083 @default.
- W2597156919 hasConcept C50382708 @default.
- W2597156919 hasConcept C71924100 @default.
- W2597156919 hasConcept C72563966 @default.
- W2597156919 hasConcept C86803240 @default.
- W2597156919 hasConcept C90924648 @default.
- W2597156919 hasConceptScore W2597156919C121608353 @default.
- W2597156919 hasConceptScore W2597156919C126322002 @default.
- W2597156919 hasConceptScore W2597156919C142724271 @default.
- W2597156919 hasConceptScore W2597156919C143998085 @default.
- W2597156919 hasConceptScore W2597156919C146357865 @default.
- W2597156919 hasConceptScore W2597156919C151730666 @default.
- W2597156919 hasConceptScore W2597156919C2779720271 @default.
- W2597156919 hasConceptScore W2597156919C2780849966 @default.
- W2597156919 hasConceptScore W2597156919C29456083 @default.
- W2597156919 hasConceptScore W2597156919C50382708 @default.
- W2597156919 hasConceptScore W2597156919C71924100 @default.
- W2597156919 hasConceptScore W2597156919C72563966 @default.
- W2597156919 hasConceptScore W2597156919C86803240 @default.
- W2597156919 hasConceptScore W2597156919C90924648 @default.
- W2597156919 hasIssue "18_suppl" @default.
- W2597156919 hasLocation W25971569191 @default.
- W2597156919 hasOpenAccess W2597156919 @default.
- W2597156919 hasPrimaryLocation W25971569191 @default.
- W2597156919 hasRelatedWork W1855068278 @default.
- W2597156919 hasRelatedWork W1993781443 @default.
- W2597156919 hasRelatedWork W2031392367 @default.
- W2597156919 hasRelatedWork W2041343500 @default.
- W2597156919 hasRelatedWork W2123141097 @default.
- W2597156919 hasRelatedWork W2395525374 @default.
- W2597156919 hasRelatedWork W2415741342 @default.
- W2597156919 hasRelatedWork W2761761118 @default.
- W2597156919 hasRelatedWork W2994537252 @default.
- W2597156919 hasRelatedWork W3029926684 @default.
- W2597156919 hasVolume "24" @default.
- W2597156919 isParatext "false" @default.
- W2597156919 isRetracted "false" @default.
- W2597156919 magId "2597156919" @default.
- W2597156919 workType "article" @default.