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- W2597218248 abstract "A novel substituted pyrenoylpyrroles was synthesized by the reaction of pyrenoyl chalcone, Tos MIC and methyl iodide under mild condition. All the synthesized compounds were screened for their bioactivity, and the MIC was determined, among which few compounds showed moderate antibacterial activity toward Gram‐positive as well as Gram‐negative bacteria. Further, cytotoxicity assay ascertained that these compounds were non‐toxic to mammalian cells as well. The pyrene chromophore in the synthesized compounds ( 3a–e ) and ( 5a–e ) is responsible for the good photophysical properties which have an absorbance at λ 340 nm and emission at λ 410 nm. Hence, two of the selected novel synthesized compounds with non‐cytotoxic nature prospected for bio‐imaging of bacterial cells using high‐content screening analysis show that the molecule is suitable for microbial imaging in pathological diagnostic studies." @default.
- W2597218248 created "2017-03-23" @default.
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- W2597218248 date "2017-05-07" @default.
- W2597218248 modified "2023-10-04" @default.
- W2597218248 title "Live cell imaging of bacterial cells: Pyrenoylpyrrole-based fluorescence labeling" @default.
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- W2597218248 doi "https://doi.org/10.1111/cbdd.12978" @default.
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