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• W259729474 abstract "The robust or model-free method for detecting linkage developed by Haseman and Elston for data from sib pairs is extended to incorporate observations of multiple traits on each individual. A method is proposed that estimates the linear function that results in the strongest correlation between the squared pair differences in the trait measurements and identity by descent at a marker locus. The method is illustrated by the study of apolipoprotein and cholesterol levels in individuals from a large family that had many members diagnosed with coronary heart disease." @default.
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• W259729474 date "1990-08-01" @default.
• W259729474 modified "2023-09-23" @default.
• W259729474 title "A multivariate method for detecting genetic linkage, with application to a pedigree with an adverse lipoprotein phenotype." @default.
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• W259729474 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1683708" @default.
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