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• W2597360772 abstract "The antimicrobial activity and toxicity to nematodes of the cyclam salt [H2{H2(4-CF3PhCH2)2Cyclam}](CH3COO)2⋅(CH3COOH)2 were evaluated. Estimated minimum inhibitory concentrations (MICs) of 9, 261 and 15 µg/mL were obtained for Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus, respectively. For selected Candida spp., the estimated MICs obtained ranged from 32 µg/mL to 63 µg/mL. Bactericidal activity was demonstrated but the compound was not reliably fungicidal. Concentrations of the cyclam salt up to 32 µg/mL did not significantly affect survival of the nematode Caenorhabditis elegans; however, concentrations equal or above this value significantly affected nematode survival in a dose-dependent manner." @default.
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• W2597360772 date "2017-05-01" @default.
• W2597360772 modified "2023-10-15" @default.
• W2597360772 title "Synthesis, antimicrobial activity and toxicity to nematodes of cyclam derivatives" @default.
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• W2597360772 doi "https://doi.org/10.1016/j.ijantimicag.2017.03.002" @default.
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