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• W2597386157 abstract "In recent years, the increasing numbers of small, apparently indolent thyroid cancers diagnosed in the world have encouraged investigators to consider non-intervention as an alternative to surgical management. In the following pages, the prospect of a non-intervention trial for thyroid cancer is considered with attention to the ethical issues that such a trial might raise. Such a non-intervention trial is analyzed relative to 7 ethical considerations: the social or scientific value of the research, the scientific validity of the trial, the necessity of fair selection of participants, a favorable risk-benefit ratio for trial participants, independent review of the trial, informed consent, and allowing the study participants to withdraw from the trial. A non-intervention trial for thyroid cancer is also considered relative to the central concept of equipoise." @default.
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• W2597386157 date "2018-03-01" @default.
• W2597386157 modified "2023-10-09" @default.
• W2597386157 title "Ethical issues in non-intervention trials for thyroid cancer" @default.
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• W2597386157 doi "https://doi.org/10.1016/j.ejso.2017.03.002" @default.
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