Matches in SemOpenAlex for { <https://semopenalex.org/work/W2597808004> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2597808004 abstract "111 Background: Thyroid cancer is the most rapidly increasing cancer with over 600,000 thyroid cancer survivors in the U.S. Thyroid cancer affects a young population and the 5-year survival rate is over 98%. There have been few studies on the late effects of thyroid cancer, especially in younger populations. The aim of this study was to examine if thyroid cancer survivors diagnosed < 40 years experience greater risks of late effects than older age groups for diseases associated with aging. Methods: Up to 5 cancer free individuals were matched to each thyroid cancer survivor based on birth year, sex, birth state, and follow up time from case diagnosis date, within the Utah Population Database. Electronic medical records, statewide ambulatory surgery and inpatient discharge data were used to identify late effects stratified over three time periods: 1-5, 5-10, and > 10 years after cancer diagnosis. Cox proportional hazards models were used to estimate hazard ratios (HR) with adjustment on matching factors, race, BMI at diagnosis, and Charlson Comorbidity Index at diagnosis. Results: There were 4,060 thyroid cancer survivors and 18,557 matched cancer free individuals (1,407 cases diagnosed ages < 40 years, 2,076 cases diagnosed ages 40-65 years). The risk for hypertension was significantly increased in both younger (HR = 1.54, 95%CI = 1.18, 2.01) and older patients (HR = 1.30, 95%CI = 1.11, 1.53) > 10 years after cancer diagnosis. For heart disease, increased risks persisted for the young patients > 10 years after cancer diagnosis for heart valve disorders (HR = 2.43, 95%CI = 1.36, 4.33) and for peri-, endo- or myocarditis (HR = 5.12, 95%CI = 1.04, 25.14), while corresponding HRs for the older age group did not suggest increased risks. For osteoporosis, the younger patients had a higher risk (HR = 8.77, 95%CI = 3.18, 24.18) than the older population (HR = 2.55, 95%CI = 2.07, 3.13) 1-5 years after cancer diagnosis. Conclusions: Thyroid cancer survivors diagnosed at < 40 years had increased risks for diseases associated with aging such as hypertension, heart disease, and osteoporosis. As thyroid cancer affects a young population, understanding what late effects may result from the treatment can lead to better surveillance and disease management." @default.
- W2597808004 created "2017-04-07" @default.
- W2597808004 creator A5000413703 @default.
- W2597808004 creator A5006824090 @default.
- W2597808004 creator A5022770821 @default.
- W2597808004 creator A5031742666 @default.
- W2597808004 creator A5037111300 @default.
- W2597808004 creator A5048328069 @default.
- W2597808004 creator A5049615387 @default.
- W2597808004 creator A5049755678 @default.
- W2597808004 creator A5052259818 @default.
- W2597808004 creator A5054574855 @default.
- W2597808004 creator A5070980712 @default.
- W2597808004 creator A5074698336 @default.
- W2597808004 creator A5085543314 @default.
- W2597808004 creator A5087047922 @default.
- W2597808004 date "2017-02-10" @default.
- W2597808004 modified "2023-09-27" @default.
- W2597808004 title "Late effects among young thyroid cancer survivors." @default.
- W2597808004 doi "https://doi.org/10.1200/jco.2017.35.5_suppl.111" @default.
- W2597808004 hasPublicationYear "2017" @default.
- W2597808004 type Work @default.
- W2597808004 sameAs 2597808004 @default.
- W2597808004 citedByCount "1" @default.
- W2597808004 countsByYear W25978080042017 @default.
- W2597808004 crossrefType "journal-article" @default.
- W2597808004 hasAuthorship W2597808004A5000413703 @default.
- W2597808004 hasAuthorship W2597808004A5006824090 @default.
- W2597808004 hasAuthorship W2597808004A5022770821 @default.
- W2597808004 hasAuthorship W2597808004A5031742666 @default.
- W2597808004 hasAuthorship W2597808004A5037111300 @default.
- W2597808004 hasAuthorship W2597808004A5048328069 @default.
- W2597808004 hasAuthorship W2597808004A5049615387 @default.
- W2597808004 hasAuthorship W2597808004A5049755678 @default.
- W2597808004 hasAuthorship W2597808004A5052259818 @default.
- W2597808004 hasAuthorship W2597808004A5054574855 @default.
- W2597808004 hasAuthorship W2597808004A5070980712 @default.
- W2597808004 hasAuthorship W2597808004A5074698336 @default.
- W2597808004 hasAuthorship W2597808004A5085543314 @default.
- W2597808004 hasAuthorship W2597808004A5087047922 @default.
- W2597808004 hasConcept C121608353 @default.
- W2597808004 hasConcept C126322002 @default.
- W2597808004 hasConcept C143998085 @default.
- W2597808004 hasConcept C207103383 @default.
- W2597808004 hasConcept C2779761222 @default.
- W2597808004 hasConcept C2908647359 @default.
- W2597808004 hasConcept C44249647 @default.
- W2597808004 hasConcept C50382708 @default.
- W2597808004 hasConcept C526584372 @default.
- W2597808004 hasConcept C71924100 @default.
- W2597808004 hasConcept C99454951 @default.
- W2597808004 hasConceptScore W2597808004C121608353 @default.
- W2597808004 hasConceptScore W2597808004C126322002 @default.
- W2597808004 hasConceptScore W2597808004C143998085 @default.
- W2597808004 hasConceptScore W2597808004C207103383 @default.
- W2597808004 hasConceptScore W2597808004C2779761222 @default.
- W2597808004 hasConceptScore W2597808004C2908647359 @default.
- W2597808004 hasConceptScore W2597808004C44249647 @default.
- W2597808004 hasConceptScore W2597808004C50382708 @default.
- W2597808004 hasConceptScore W2597808004C526584372 @default.
- W2597808004 hasConceptScore W2597808004C71924100 @default.
- W2597808004 hasConceptScore W2597808004C99454951 @default.
- W2597808004 hasLocation W25978080041 @default.
- W2597808004 hasOpenAccess W2597808004 @default.
- W2597808004 hasPrimaryLocation W25978080041 @default.
- W2597808004 hasRelatedWork W1528633279 @default.
- W2597808004 hasRelatedWork W1563440520 @default.
- W2597808004 hasRelatedWork W1950402214 @default.
- W2597808004 hasRelatedWork W195937730 @default.
- W2597808004 hasRelatedWork W2016538989 @default.
- W2597808004 hasRelatedWork W2056421762 @default.
- W2597808004 hasRelatedWork W2100270585 @default.
- W2597808004 hasRelatedWork W2142838998 @default.
- W2597808004 hasRelatedWork W2364590242 @default.
- W2597808004 hasRelatedWork W240381833 @default.
- W2597808004 hasRelatedWork W2803699401 @default.
- W2597808004 hasRelatedWork W2888520432 @default.
- W2597808004 hasRelatedWork W2889984398 @default.
- W2597808004 hasRelatedWork W2933634079 @default.
- W2597808004 hasRelatedWork W2940327689 @default.
- W2597808004 hasRelatedWork W2943073652 @default.
- W2597808004 hasRelatedWork W3030486308 @default.
- W2597808004 hasRelatedWork W3137352051 @default.
- W2597808004 hasRelatedWork W3157611122 @default.
- W2597808004 hasRelatedWork W3192242868 @default.
- W2597808004 isParatext "false" @default.
- W2597808004 isRetracted "false" @default.
- W2597808004 magId "2597808004" @default.
- W2597808004 workType "article" @default.