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- W2597966165 abstract "We have previously identified association of 6 singlenucleotide polymorphisms (SNP) with diabetic nephropathy (DN)in type 2 diabetes mellitus (T2DM) using multi-locus analysisin a case – control study comprising 419 type 2 diabetics and228 healthy subjects genotyped for 45 SNPs in 20 candidategenes for DN. We identified SNPs in four genes – AGER (-429T>Cand 2184A>G), EDN1 (8002G>A) and LTA (252A>G) on chromosome 6pand NOS3 (774C>T and 894G>T) on chromosome 7q - associated withDN in T2DM. In the present study we genotyped the same SNPs inthe independent cohort of prospectively followed T2DM patientswith aim to investigate their possible role in the progressionof DN and development of morbidity and mortality associatedwith diabetes." @default.
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- W2597966165 date "2013-10-31" @default.
- W2597966165 modified "2023-10-18" @default.
- W2597966165 title "NOS3 polymorphisms are associated with progression of kidneyand cardiovascular disease in type 2 diabetic patients" @default.
- W2597966165 hasPublicationYear "2013" @default.
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