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• W2598097006 abstract "Chronic obstructive pulmonary disease (COPD) is common worldwide. The predominant cause in most COPD is environmental exposure to toxicants. The inflammatory processes in COPD are multifactorial, complex, and interacting, leading to many potential therapeutic targets. Although most typically associated with neutrophilic/macrophagic inflammation (type 1), it is now known that COPD can also be associated with eosinophilic inflammation (type 2), particularly in exacerbations. Accordingly, there is an active program of investigation of highly selective biologic therapeutic agents in the management of COPD. This review summarizes clinical trials of the use of these novel agents in the management of COPD." @default.
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• W2598097006 date "2017-05-01" @default.
• W2598097006 modified "2023-09-24" @default.
• W2598097006 title "Biologic Therapy in Chronic Obstructive Pulmonary Disease" @default.
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• W2598097006 doi "https://doi.org/10.1016/j.iac.2017.01.009" @default.
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