FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2598332901> ?p ?o ?g. }

• W2598332901 endingPage "321" @default.
• W2598332901 startingPage "321" @default.
• W2598332901 abstract "Background and aims: Dietary studies have shown that active biopeptides provide protective health benefits, although the mediating pathways are somewhat uncertain. To throw light on this situation, we studied the effects of consuming Spanish dry-cured ham on platelet function, monocyte activation markers and the inflammatory status of healthy humans with pre-hypertension. Methods: Thirty-eight healthy volunteers with systolic blood pressure of >125 mmHg were enrolled in a two-arm crossover randomized controlled trial. Participants received 80 g/day dry-cured pork ham of >11 months proteolysis or 100 g/day cooked ham (control product) for 4 weeks followed by a 2-week washout before “crossing over” to the other treatment for 4 more weeks. Soluble markers and cytokines were analyzed by ELISA. Platelet function was assessed by measuring P-selectin expression and PAC-1 binding after ADP (adenosine diphosphate) stimulation using whole blood flow cytometry. Monocyte markers of the pathological status (adhesion, inflammatory and scavenging receptors) were also measured by flow cytometry in the three monocyte subsets after the interventional period. Results: The mean differences between dry-cured ham and cooked ham followed by a time period adjustment for plasmatic P-selectin and interleukin 6 proteins slightly failed (p = 0.062 and p = 0.049, respectively), notably increased for MCP-1 levels (p = 0.023) while VCAM-1 was not affected. Platelet function also decreased after ADP stimulation. The expression of adhesion and scavenging markers (ICAM1R, CXCR4 and TLR4) in the three subsets of monocytes was significantly higher (all p < 0.05). Conclusions: The regular consumption of biopeptides contained in the dry-cured ham but absent in cooked ham impaired platelet and monocyte activation and the levels of plasmatic P-selectin, MCP-1 and interleukin 6 in healthy subjects. This study strongly suggests the existence of a mechanism that links dietary biopeptides and beneficial health effects." @default.
• W2598332901 created "2017-04-07" @default.
• W2598332901 creator A5003922771 @default.
• W2598332901 creator A5009033229 @default.
• W2598332901 creator A5051185129 @default.
• W2598332901 creator A5052865465 @default.
• W2598332901 creator A5086236489 @default.
• W2598332901 creator A5089000721 @default.
• W2598332901 date "2017-03-23" @default.
• W2598332901 modified "2023-10-16" @default.
• W2598332901 title "The Effect of Regular Intake of Dry-Cured Ham Rich in Bioactive Peptides on Inflammation, Platelet and Monocyte Activation Markers in Humans" @default.
• W2598332901 cites W1493858061 @default.
• W2598332901 cites W1800020109 @default.
• W2598332901 cites W1978051575 @default.
• W2598332901 cites W1999897292 @default.
• W2598332901 cites W2011158744 @default.
• W2598332901 cites W2012841382 @default.
• W2598332901 cites W2023455126 @default.
• W2598332901 cites W2034819178 @default.
• W2598332901 cites W2037428083 @default.
• W2598332901 cites W2039514094 @default.
• W2598332901 cites W2043734508 @default.
• W2598332901 cites W2046040114 @default.
• W2598332901 cites W2048430281 @default.
• W2598332901 cites W2054530987 @default.
• W2598332901 cites W2057971692 @default.
• W2598332901 cites W2059677284 @default.
• W2598332901 cites W2061367553 @default.
• W2598332901 cites W2067208148 @default.
• W2598332901 cites W2068886931 @default.
• W2598332901 cites W2080797635 @default.
• W2598332901 cites W2084158483 @default.
• W2598332901 cites W2096431838 @default.
• W2598332901 cites W2099551200 @default.
• W2598332901 cites W2110641306 @default.
• W2598332901 cites W2113667205 @default.
• W2598332901 cites W2131367671 @default.
• W2598332901 cites W2171646117 @default.
• W2598332901 cites W2280379511 @default.
• W2598332901 cites W564798388 @default.
• W2598332901 doi "https://doi.org/10.3390/nu9040321" @default.
• W2598332901 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5409660" @default.
• W2598332901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28333093" @default.
• W2598332901 hasPublicationYear "2017" @default.
• W2598332901 type Work @default.
• W2598332901 sameAs 2598332901 @default.
• W2598332901 citedByCount "25" @default.
• W2598332901 countsByYear W25983329012017 @default.
• W2598332901 countsByYear W25983329012018 @default.
• W2598332901 countsByYear W25983329012019 @default.
• W2598332901 countsByYear W25983329012020 @default.
• W2598332901 countsByYear W25983329012021 @default.
• W2598332901 countsByYear W25983329012022 @default.
• W2598332901 countsByYear W25983329012023 @default.
• W2598332901 crossrefType "journal-article" @default.
• W2598332901 hasAuthorship W2598332901A5003922771 @default.
• W2598332901 hasAuthorship W2598332901A5009033229 @default.
• W2598332901 hasAuthorship W2598332901A5051185129 @default.
• W2598332901 hasAuthorship W2598332901A5052865465 @default.
• W2598332901 hasAuthorship W2598332901A5086236489 @default.
• W2598332901 hasAuthorship W2598332901A5089000721 @default.
• W2598332901 hasBestOaLocation W25983329011 @default.
• W2598332901 hasConcept C126322002 @default.
• W2598332901 hasConcept C134018914 @default.
• W2598332901 hasConcept C142724271 @default.
• W2598332901 hasConcept C203014093 @default.
• W2598332901 hasConcept C204787440 @default.
• W2598332901 hasConcept C24998067 @default.
• W2598332901 hasConcept C27081682 @default.
• W2598332901 hasConcept C2776914184 @default.
• W2598332901 hasConcept C2781184567 @default.
• W2598332901 hasConcept C3018697912 @default.
• W2598332901 hasConcept C553184892 @default.
• W2598332901 hasConcept C71924100 @default.
• W2598332901 hasConcept C87813604 @default.
• W2598332901 hasConcept C89560881 @default.
• W2598332901 hasConceptScore W2598332901C126322002 @default.
• W2598332901 hasConceptScore W2598332901C134018914 @default.
• W2598332901 hasConceptScore W2598332901C142724271 @default.
• W2598332901 hasConceptScore W2598332901C203014093 @default.
• W2598332901 hasConceptScore W2598332901C204787440 @default.
• W2598332901 hasConceptScore W2598332901C24998067 @default.
• W2598332901 hasConceptScore W2598332901C27081682 @default.
• W2598332901 hasConceptScore W2598332901C2776914184 @default.
• W2598332901 hasConceptScore W2598332901C2781184567 @default.
• W2598332901 hasConceptScore W2598332901C3018697912 @default.
• W2598332901 hasConceptScore W2598332901C553184892 @default.
• W2598332901 hasConceptScore W2598332901C71924100 @default.
• W2598332901 hasConceptScore W2598332901C87813604 @default.
• W2598332901 hasConceptScore W2598332901C89560881 @default.
• W2598332901 hasFunder F4320320300 @default.
• W2598332901 hasIssue "4" @default.
• W2598332901 hasLocation W25983329011 @default.
• W2598332901 hasLocation W25983329012 @default.
• W2598332901 hasLocation W25983329013 @default.
• W2598332901 hasLocation W25983329014 @default.
• W2598332901 hasLocation W25983329015 @default.
• W2598332901 hasLocation W25983329016 @default.

• next