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- W2598486519 abstract "e20597 Background: Cancer patients experience multiple symptoms which vary in prevalence, severity, distress and negative impact on life. Comprehensive assessment is essential. Many validated assessment tools are used. They have limitations; varied content, clinical utility, completion rates, and acceptability. The objectives of this study were: Compare common cancer multisymptom assessment instruments to a comprehensive checklist. Identify commonly assessed (“champions”) and frequently neglected (“orphans”) symptoms. Examine the clinical importance of “orphan” symptoms. Methods: A 46-symptom checklist was developed from available evidence. This was compared against the content of 6 commonly used, validated, multisymptom instruments. Those with ≤ 2 symptoms, cancer site-specific, and tumor response instruments were excluded. Results: Symptom numbers varied in the 6 instruments; median (range) 19 (3-32). Of the 46 checklist symptoms, only 28 were present in 1 or more of the instruments. “Orphans”: 18 of the 46 were not evaluated in any of the 6 (e.g., confusion, agitation, early satiety, indigestion, tremors). 12 of the 18 had prevalence rates >10%. These symptoms are also often rated moderate/severe and distressful. “Champions”: Only four checklist symptoms (pain, fatigue, dyspnea, anorexia) were present in all 6 instruments. Conclusions: Eighteen “orphan” symptoms (severe/distressing) were not captured by any tool. Only four “champion” symptoms were present in all validated tools. Unreported and misdiagnosed symptoms can bias our view of the cancer symptom experience. Validated cancer symptom assessment tools do not capture accurate, reliable comprehensive data on the cancer symptom experience. These challenge the validity and reliability of current symptom assessment tools in clinical research." @default.
- W2598486519 created "2017-04-07" @default.
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- W2598486519 date "2013-05-20" @default.
- W2598486519 modified "2023-09-24" @default.
- W2598486519 title "Are validated symptom assessment instruments comprehensive? “Orphan” and “champion” symptoms." @default.
- W2598486519 doi "https://doi.org/10.1200/jco.2013.31.15_suppl.e20597" @default.
- W2598486519 hasPublicationYear "2013" @default.
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