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- W2598497657 abstract "Abstract Nowadays, there is an upsurge of interest on finding effective phyto-constituents as new sources of natural antioxidants for using in food and pharmaceutical preparations. However, this study was carried out to investigate the antioxidant and free radical scavenging efficacy of a biologically active diterpenoid compound taxoquinone isolated from Metasequoia glyptostroboides in various antioxidant models. An abietane type diterpenoid taxoquinone, isolated from ethyl acetate cone extract of Metasequoia glyptostroboides , was analyzed for its antioxidant efficacy as reducing power ability and its ability to scavenge free radicals such as 1,1-diphenyl-2-picryl hydrazyl (DPPH), nitric oxide, superoxide and hydroxyl radicals. As a result, taxoquinone showed significant and concentration-dependent antioxidant and free radical scavenging activities of DPPH, nitric oxide, superoxide and hydroxyl free radicals by 78.83%, 72.42%, 72.99% and 85.04%, as compared to standard compounds ascorbic acid (81.69%, 74.62%, 73% and 73.79%) and α-tocopherol/butylated hydroxyanisole (84.09%, 78.61%, 74.45% and 70.02%), respectively. These findings justify the biological and traditional uses of M. glyptostroboides or its secondary metabolite taxoquinone as confirmed by its promising antioxidant and free radical scavenging activities." @default.
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- W2598497657 date "2017-07-01" @default.
- W2598497657 modified "2023-09-27" @default.
- W2598497657 title "Antioxidant and free radical scavenging activities of taxoquinone, a diterpenoid isolated from Metasequoia glyptostroboides" @default.
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- W2598497657 doi "https://doi.org/10.1016/j.sajb.2017.03.004" @default.
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