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- W2598515809 abstract "Inflammatory bowel disease (IBD) is the consequence of an aberrant hemostasis of the immune cells at the gut mucosal border. Based on clinical manifestation, laboratory tests, radiological studies, endoscopic and histological features, this disease is divided into three main types including Crohn’s disease (CD), Ulcerative colitis (UC), and IBDunclassified (IBD-U). IBD is frequently presented in adults, but about 20% of IBD cases are diagnosed during childhood called pediatric IBD (PIBD). Some patients in the latter group emerge the first symptoms during infancy or under 5 years of age named infantile and very early onset IBD (VEO-IBD), respectively. These subtypes make a small fraction of PIBD, but they have exclusive phenotypic and genetic characteristics such that they are accompanied by severe disease course and resistance to conventional therapy. In this context, understanding the underlying molecular pathology opens a promising field for individualized and effective treatment. Here, we describe current hypotheses on IBD pathophysiology then explain the new idea about genetic screening technology as a good potential approach to identify the causal variants early in the disease manifestation, which is especially important for the fast and accurate treatment of VEO-IBD." @default.
- W2598515809 created "2017-04-07" @default.
- W2598515809 creator A5060269775 @default.
- W2598515809 creator A5081821246 @default.
- W2598515809 date "2017-02-03" @default.
- W2598515809 modified "2023-10-06" @default.
- W2598515809 title "An Overview of Inflammatory Bowel Disease: General Consideration and Genetic Screening Approach in Diagnosis of Early Onset Subsets" @default.
- W2598515809 cites W1014257459 @default.
- W2598515809 cites W1492322782 @default.
- W2598515809 cites W1964182398 @default.
- W2598515809 cites W1964428715 @default.
- W2598515809 cites W1965655960 @default.
- W2598515809 cites W1967217097 @default.
- W2598515809 cites W1968797543 @default.
- W2598515809 cites W1968850709 @default.
- W2598515809 cites W1971929027 @default.
- W2598515809 cites W1982307886 @default.
- W2598515809 cites W1989033960 @default.
- W2598515809 cites W1991886741 @default.
- W2598515809 cites W1996933969 @default.
- W2598515809 cites W1997312045 @default.
- W2598515809 cites W2001294018 @default.
- W2598515809 cites W2004608617 @default.
- W2598515809 cites W2006194008 @default.
- W2598515809 cites W2008250059 @default.
- W2598515809 cites W2010396903 @default.
- W2598515809 cites W2014467362 @default.
- W2598515809 cites W2018774199 @default.
- W2598515809 cites W2021174967 @default.
- W2598515809 cites W2022752303 @default.
- W2598515809 cites W2029791051 @default.
- W2598515809 cites W2031702687 @default.
- W2598515809 cites W2034950109 @default.
- W2598515809 cites W2036109191 @default.
- W2598515809 cites W2042501166 @default.
- W2598515809 cites W2047208232 @default.
- W2598515809 cites W2051007260 @default.
- W2598515809 cites W2051039710 @default.
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- W2598515809 doi "https://doi.org/10.15171/mejdd.2017.54" @default.
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