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- W2598543357 abstract "by histologic examination of the tissue involved. In the majority of instances palpably enlarged superficial lymph nodes are present and properly performed biopsy provides the correct diagnosis in a direct and relatively simple manner. However, in a significant number of cases of Hodgkin’s disease, lymphosarcoma 4 and follicular lymphoma the primary site of involvement is thoracic, abdominal or some otherwise inaccessible location for simple biopsy. Symmers’ has stated that in Hodgkin’s disease primary enlargement of abdominal or of abdominal and thoracic nodes combined is ten times more common than primary enlargement of the cervical nodes. Ewing2 supported this view, emphasizing that the superficial nodes which first attract attention may be only the outlying manifestations of an internal lesion. Jackson and Parker3 found the superficial nodes primarily involved in all of 2.6 cases of Hodgkin’s ‘�aragranuloma, but in only 8 of 59 cases of Hodgkin’s granuloma, and in none of 2.7 cases of Hodgkin’s sarcoma. Sugarbaker and Craver4 regarded the primary site of involvement as extranodal in approximately one third of cent of cases in which lymph nodes were involved primarily, the site of origin was abdominal or mediastinal. These observations contrast clearly with the common impression that superficial lymph nodes, particularly those of the cervical area, constitute the usual site of primary involvement in these conditions. Biopsy of superficial nodes, then, may be of no value in establishing a diagnosis in some cases and of value only after the disease process is well advanced in others. This study was undertaken in an attempt to evaluate the clinical usefulness of aspiration of sternal bone marrow as a method for obtaining material of diagnostic significance in cases ofmalignant lymphoma." @default.
- W2598543357 created "2017-04-07" @default.
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- W2598543357 date "2017-01-01" @default.
- W2598543357 modified "2023-09-27" @default.
- W2598543357 title "T HE DIAGNOSIS of malignant lymphoma can be definitely established only" @default.
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