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- W2598673721 abstract "Zinc oxide nanograss (ZnONG) decorated with gold (Au) nanospeckles is demonstrated as a sensing platform for bacterial DNA hybridization in this study. Thermal evaporation of 5 nm Au on hydrothermally synthesized ZnONG generates highly dense speckles, which contributes to an approximately two-fold enhancement of the effective surface area and diffusion coefficient in cyclic voltammetry (CV) measurement compared to the non-speckled nanograss. Selective capture of molecular probes from our predesigned sequence of S. epidermidis 16S rRNA onto nanospeckled ZnONG indicated a specific interaction with the DNA target from this prevalently isolated skin pathogen through hybridization screening. The fabricated DNA biosensor demonstrated great ability to quantify a wide range of complementary DNA target, from 10 pM to 1 μM. Moreover, it attained an impressive limit of detection (LOD) of 0.506 pM, as determined by the charge-transfer resistance (RCT), upon DNA hybridization in an electrochemical impedance spectroscopy (EIS) analysis. The proposed structure of the hybrid Au-speckled ZnONG effectively improved the electro-catalytic properties and electron migration of electrochemical DNA detection due to the increment of the surface area, which consequently renders this structure a potential platform for array-based DNA sensor development." @default.
- W2598673721 created "2017-04-07" @default.
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- W2598673721 date "2017-01-01" @default.
- W2598673721 modified "2023-10-17" @default.
- W2598673721 title "Speckled ZnO Nanograss Electrochemical Sensor for<i>Staphylococcus epidermidis</i>Detection" @default.
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- W2598673721 doi "https://doi.org/10.1149/2.0811706jes" @default.
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