Matches in SemOpenAlex for { <https://semopenalex.org/work/W2598793742> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2598793742 abstract "e19614 Background: There are some known risk factors for deep vein thrombosis in cancer patients, such as primary site of cancer, white blood cell count (WBC), hemoglobin (Hb), platelet count (PLT). We investigated the association between these factors and the overall survival as prognostic factor in gastrointestinal (GI) cancer patients. Methods: All the patients with gastrointestinal cancer, who developed deep vein thrombosis or pulmonary thromboembolism through the clinical course, were retrospectively reviewed between January 2009 and June 2011 at Seoul St. Mary’s Hospital. According to treatment, patients were classified into two groups; the chemotherapy group and the supportive care group. Results: Of the fifty-six patients, median age was sixty three year-old. Stomach cancer was most common 35% , pancreatic cancer 31%, colorectal cancer 19%, and biliary cancer was 15%. There were three pattern of thrombosis: 19 (34%) deep vein thrombosis (DVT) only, 12 (21%) pulmonary thromboembolism (PTE) only, 25 (45%) combined DVT with PTE. WBC count above 11,000/µ° showed the poor overall survival than other group (median survival 3.4 months vs. 1.7 months, respectively, p=0.015) However, other risk factor did not show any significant association (Hb: p=0.521, PLT: p=0.295) In chemotherapy group, twelve (55%) patients had progressive disease and ten (45%) patients had stable disease at the time of thrombotic event. There was no statistically significant association between thrombosis and tumor response. The chemotherapy group had tendency of better survival outcome than the supportive care group without statistical significance (median survival 2.4 months vs. 5.3months, p=0.07). Conclusions: In GI cancer patients, elevated white blood cell count above 11,000/µ° can be important prognostic and risk factor for thrombosis with poor survival outcome. And the response of chemotherapy seemed to have no influence on thrombotic event during chemotherapy. This is very limited study due to small sample size and retrospective analysis, and heterogenous type of cancer. Further large study should be warranted to define the thrombotic risk factor as prognostic marker." @default.
- W2598793742 created "2017-04-07" @default.
- W2598793742 creator A5000487712 @default.
- W2598793742 creator A5014474281 @default.
- W2598793742 creator A5023344582 @default.
- W2598793742 creator A5042102327 @default.
- W2598793742 creator A5048033504 @default.
- W2598793742 date "2012-05-20" @default.
- W2598793742 modified "2023-09-27" @default.
- W2598793742 title "Use of high white blood cell (WBC) count to predict poor survival outcome in gastrointestinal (GI) cancer with thrombotic event." @default.
- W2598793742 doi "https://doi.org/10.1200/jco.2012.30.15_suppl.e19614" @default.
- W2598793742 hasPublicationYear "2012" @default.
- W2598793742 type Work @default.
- W2598793742 sameAs 2598793742 @default.
- W2598793742 citedByCount "0" @default.
- W2598793742 crossrefType "journal-article" @default.
- W2598793742 hasAuthorship W2598793742A5000487712 @default.
- W2598793742 hasAuthorship W2598793742A5014474281 @default.
- W2598793742 hasAuthorship W2598793742A5023344582 @default.
- W2598793742 hasAuthorship W2598793742A5042102327 @default.
- W2598793742 hasAuthorship W2598793742A5048033504 @default.
- W2598793742 hasConcept C121608353 @default.
- W2598793742 hasConcept C126322002 @default.
- W2598793742 hasConcept C143998085 @default.
- W2598793742 hasConcept C2778488018 @default.
- W2598793742 hasConcept C2778917026 @default.
- W2598793742 hasConcept C2778959117 @default.
- W2598793742 hasConcept C2779979121 @default.
- W2598793742 hasConcept C2780868729 @default.
- W2598793742 hasConcept C526805850 @default.
- W2598793742 hasConcept C542804219 @default.
- W2598793742 hasConcept C71924100 @default.
- W2598793742 hasConcept C89560881 @default.
- W2598793742 hasConcept C90924648 @default.
- W2598793742 hasConceptScore W2598793742C121608353 @default.
- W2598793742 hasConceptScore W2598793742C126322002 @default.
- W2598793742 hasConceptScore W2598793742C143998085 @default.
- W2598793742 hasConceptScore W2598793742C2778488018 @default.
- W2598793742 hasConceptScore W2598793742C2778917026 @default.
- W2598793742 hasConceptScore W2598793742C2778959117 @default.
- W2598793742 hasConceptScore W2598793742C2779979121 @default.
- W2598793742 hasConceptScore W2598793742C2780868729 @default.
- W2598793742 hasConceptScore W2598793742C526805850 @default.
- W2598793742 hasConceptScore W2598793742C542804219 @default.
- W2598793742 hasConceptScore W2598793742C71924100 @default.
- W2598793742 hasConceptScore W2598793742C89560881 @default.
- W2598793742 hasConceptScore W2598793742C90924648 @default.
- W2598793742 hasLocation W25987937421 @default.
- W2598793742 hasOpenAccess W2598793742 @default.
- W2598793742 hasPrimaryLocation W25987937421 @default.
- W2598793742 hasRelatedWork W1785304382 @default.
- W2598793742 hasRelatedWork W1982267544 @default.
- W2598793742 hasRelatedWork W2140125972 @default.
- W2598793742 hasRelatedWork W2141681288 @default.
- W2598793742 hasRelatedWork W2144647124 @default.
- W2598793742 hasRelatedWork W2170949758 @default.
- W2598793742 hasRelatedWork W2357325948 @default.
- W2598793742 hasRelatedWork W2359423946 @default.
- W2598793742 hasRelatedWork W2387218938 @default.
- W2598793742 hasRelatedWork W2590037863 @default.
- W2598793742 hasRelatedWork W2735072543 @default.
- W2598793742 hasRelatedWork W2907196366 @default.
- W2598793742 hasRelatedWork W2939015369 @default.
- W2598793742 hasRelatedWork W2980479132 @default.
- W2598793742 hasRelatedWork W2994473069 @default.
- W2598793742 hasRelatedWork W2997706373 @default.
- W2598793742 hasRelatedWork W3137459608 @default.
- W2598793742 hasRelatedWork W3194191658 @default.
- W2598793742 hasRelatedWork W3208309285 @default.
- W2598793742 hasRelatedWork W3214728537 @default.
- W2598793742 isParatext "false" @default.
- W2598793742 isRetracted "false" @default.
- W2598793742 magId "2598793742" @default.
- W2598793742 workType "article" @default.