FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2599056472> ?p ?o ?g. }

• W2599056472 endingPage "706" @default.
• W2599056472 startingPage "701" @default.
• W2599056472 abstract "We report the development of a sensitive label-free, cost-effective detection system with simultaneous multi-channel measurement of open circuit potential (OCP) variations for the detection of prostate specific antigen (PSA). We demonstrate a significant increase of 600 times in the sensitivity as compared to the reported literature. To accurately measure OCP variations, a complete monolithic field-effect transistor (FET)-input ultra-low input bias current instrumentation amplifier is used to form the electronic circuit to measure the variation between a working electrode and a reference electrode. This amplifier electronic system setup provides a differential voltage measurement with high input impedance and low input bias current. Since no current is applied to the electrochemical system, a true and accurate measurement of the variation can be performed. This is the first report on the use of DNA aptamers with an OCP system where we employed a DNA aptamer against PSA. An optimised ratio of anti-PSA DNA aptamer with 6-mercapto-1-hexanol (MCH) was used to fabricate the aptasensor using gold electrodes. The electrodes are hosted in a cell with an automated flow system. A wide range of concentrations of PSA (0.1 to 100 ng/mL) were injected through the system. The sensor could potentially differentiate 0.1 ng/mL PSA from blank measurement, which is well below the required clinical range (>1 ng/mL). The sensor was also challenged with 4% human serum albumin and human kallikrein2 as control proteins where the sensor demonstrated excellent selectivity. The developed system can be further generalised to various other targets using specific probes." @default.
• W2599056472 created "2017-04-07" @default.
• W2599056472 creator A5044193643 @default.
• W2599056472 creator A5069467963 @default.
• W2599056472 creator A5084244543 @default.
• W2599056472 date "2017-04-01" @default.
• W2599056472 modified "2023-10-15" @default.
• W2599056472 title "Development of a Sensitive Multiplexed Open Circuit Potential System for the Detection of Prostate Cancer Biomarkers" @default.
• W2599056472 cites W1007490150 @default.
• W2599056472 cites W1964405299 @default.
• W2599056472 cites W1973837500 @default.
• W2599056472 cites W1989066746 @default.
• W2599056472 cites W2001937647 @default.
• W2599056472 cites W2010546028 @default.
• W2599056472 cites W2014130791 @default.
• W2599056472 cites W2028606986 @default.
• W2599056472 cites W2034673235 @default.
• W2599056472 cites W2046988734 @default.
• W2599056472 cites W2061530854 @default.
• W2599056472 cites W2064157091 @default.
• W2599056472 cites W2077997015 @default.
• W2599056472 cites W2135324507 @default.
• W2599056472 cites W2147304776 @default.
• W2599056472 cites W2159737140 @default.
• W2599056472 cites W2165171274 @default.
• W2599056472 cites W2335679869 @default.
• W2599056472 cites W2417258148 @default.
• W2599056472 cites W368895626 @default.
• W2599056472 doi "https://doi.org/10.1007/s12668-017-0408-0" @default.
• W2599056472 hasPublicationYear "2017" @default.
• W2599056472 type Work @default.
• W2599056472 sameAs 2599056472 @default.
• W2599056472 citedByCount "13" @default.
• W2599056472 countsByYear W25990564722017 @default.
• W2599056472 countsByYear W25990564722018 @default.
• W2599056472 countsByYear W25990564722019 @default.
• W2599056472 countsByYear W25990564722020 @default.
• W2599056472 countsByYear W25990564722021 @default.
• W2599056472 countsByYear W25990564722022 @default.
• W2599056472 countsByYear W25990564722023 @default.
• W2599056472 crossrefType "journal-article" @default.
• W2599056472 hasAuthorship W2599056472A5044193643 @default.
• W2599056472 hasAuthorship W2599056472A5069467963 @default.
• W2599056472 hasAuthorship W2599056472A5084244543 @default.
• W2599056472 hasBestOaLocation W25990564722 @default.
• W2599056472 hasConcept C119599485 @default.
• W2599056472 hasConcept C127413603 @default.
• W2599056472 hasConcept C128972844 @default.
• W2599056472 hasConcept C136229726 @default.
• W2599056472 hasConcept C147789679 @default.
• W2599056472 hasConcept C165801399 @default.
• W2599056472 hasConcept C172385210 @default.
• W2599056472 hasConcept C17525397 @default.
• W2599056472 hasConcept C185592680 @default.
• W2599056472 hasConcept C192562407 @default.
• W2599056472 hasConcept C194257627 @default.
• W2599056472 hasConcept C24326235 @default.
• W2599056472 hasConcept C41008148 @default.
• W2599056472 hasConcept C46362747 @default.
• W2599056472 hasConcept C49040817 @default.
• W2599056472 hasConcept C54355233 @default.
• W2599056472 hasConcept C86803240 @default.
• W2599056472 hasConceptScore W2599056472C119599485 @default.
• W2599056472 hasConceptScore W2599056472C127413603 @default.
• W2599056472 hasConceptScore W2599056472C128972844 @default.
• W2599056472 hasConceptScore W2599056472C136229726 @default.
• W2599056472 hasConceptScore W2599056472C147789679 @default.
• W2599056472 hasConceptScore W2599056472C165801399 @default.
• W2599056472 hasConceptScore W2599056472C172385210 @default.
• W2599056472 hasConceptScore W2599056472C17525397 @default.
• W2599056472 hasConceptScore W2599056472C185592680 @default.
• W2599056472 hasConceptScore W2599056472C192562407 @default.
• W2599056472 hasConceptScore W2599056472C194257627 @default.
• W2599056472 hasConceptScore W2599056472C24326235 @default.
• W2599056472 hasConceptScore W2599056472C41008148 @default.
• W2599056472 hasConceptScore W2599056472C46362747 @default.
• W2599056472 hasConceptScore W2599056472C49040817 @default.
• W2599056472 hasConceptScore W2599056472C54355233 @default.
• W2599056472 hasConceptScore W2599056472C86803240 @default.
• W2599056472 hasFunder F4320334960 @default.
• W2599056472 hasIssue "2" @default.
• W2599056472 hasLocation W25990564721 @default.
• W2599056472 hasLocation W25990564722 @default.
• W2599056472 hasLocation W25990564723 @default.
• W2599056472 hasOpenAccess W2599056472 @default.
• W2599056472 hasPrimaryLocation W25990564721 @default.
• W2599056472 hasRelatedWork W1970773045 @default.
• W2599056472 hasRelatedWork W2033684641 @default.
• W2599056472 hasRelatedWork W2081632393 @default.
• W2599056472 hasRelatedWork W2147509954 @default.
• W2599056472 hasRelatedWork W2390834423 @default.
• W2599056472 hasRelatedWork W2620580795 @default.
• W2599056472 hasRelatedWork W2898457449 @default.
• W2599056472 hasRelatedWork W2913646003 @default.
• W2599056472 hasRelatedWork W2967136651 @default.
• W2599056472 hasRelatedWork W2990980575 @default.
• W2599056472 hasVolume "8" @default.
• W2599056472 isParatext "false" @default.

• next