FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2599120840> ?p ?o ?g. }

• W2599120840 endingPage "359" @default.
• W2599120840 startingPage "350" @default.
• W2599120840 abstract "Since the discovery of c-di-GMP almost three decades ago, cyclic dinucleotides (CDNs) have emerged as widely used signaling molecules in most kingdoms of life. The family of second messengers now includes c-di-AMP and distinct versions of mixed cyclic GMP-AMP (cGAMP) compounds. In addition to these nucleotides, a vast number of proteins for the production and turnover of these molecules have been described, as well as effectors that translate the signals into physiological responses. The latter include, but are not limited to, mechanisms for adaptation and survival in prokaryotes, persistence and virulence of bacterial pathogens, and immune responses to viral and bacterial invasion in eukaryotes. In this review, we will focus on recent discoveries and emerging themes that illustrate the ubiquity and versatility of cyclic dinucleotide function at the transcriptional and post-translational levels and, in particular, on insights gained through mechanistic structure-function analyses. A review of the roles of cyclic dinucleotides (CDNs) in signaling systems including transcription, ion transport, bacterial secretion and eukaryotic immune responses, highlighting the diverse binding modes of CDNs by target proteins and functional insights gained from structural studies." @default.
• W2599120840 created "2017-04-07" @default.
• W2599120840 creator A5013510837 @default.
• W2599120840 creator A5028476200 @default.
• W2599120840 date "2017-03-22" @default.
• W2599120840 modified "2023-10-01" @default.
• W2599120840 title "Versatile modes of cellular regulation via cyclic dinucleotides" @default.
• W2599120840 cites W1559117436 @default.
• W2599120840 cites W1576348920 @default.
• W2599120840 cites W1780853035 @default.
• W2599120840 cites W1822002560 @default.
• W2599120840 cites W1830488268 @default.
• W2599120840 cites W1886214354 @default.
• W2599120840 cites W1890914571 @default.
• W2599120840 cites W1903069786 @default.
• W2599120840 cites W1933048492 @default.
• W2599120840 cites W1943352883 @default.
• W2599120840 cites W1965643794 @default.
• W2599120840 cites W1967562956 @default.
• W2599120840 cites W1973456850 @default.
• W2599120840 cites W1976347829 @default.
• W2599120840 cites W1977991437 @default.
• W2599120840 cites W1983029663 @default.
• W2599120840 cites W1990657825 @default.
• W2599120840 cites W1991658240 @default.
• W2599120840 cites W1993860509 @default.
• W2599120840 cites W1998907151 @default.
• W2599120840 cites W2001774544 @default.
• W2599120840 cites W2003034886 @default.
• W2599120840 cites W2004938907 @default.
• W2599120840 cites W2006757381 @default.
• W2599120840 cites W2010787284 @default.
• W2599120840 cites W2016965453 @default.
• W2599120840 cites W2021364411 @default.
• W2599120840 cites W2039390702 @default.
• W2599120840 cites W2041345682 @default.
• W2599120840 cites W2041355006 @default.
• W2599120840 cites W2042975167 @default.
• W2599120840 cites W2046713164 @default.
• W2599120840 cites W2048423752 @default.
• W2599120840 cites W2052618033 @default.
• W2599120840 cites W2052886836 @default.
• W2599120840 cites W2054871938 @default.
• W2599120840 cites W2055063197 @default.
• W2599120840 cites W2061670564 @default.
• W2599120840 cites W2065652119 @default.
• W2599120840 cites W2066586758 @default.
• W2599120840 cites W2066818317 @default.
• W2599120840 cites W2067494030 @default.
• W2599120840 cites W2069255366 @default.
• W2599120840 cites W2075660545 @default.
• W2599120840 cites W2082220748 @default.
• W2599120840 cites W2084284467 @default.
• W2599120840 cites W2086497778 @default.
• W2599120840 cites W2087017025 @default.
• W2599120840 cites W2088157683 @default.
• W2599120840 cites W2091895129 @default.
• W2599120840 cites W2093268266 @default.
• W2599120840 cites W2094144273 @default.
• W2599120840 cites W2095720959 @default.
• W2599120840 cites W2096770879 @default.
• W2599120840 cites W2098361894 @default.
• W2599120840 cites W2099610218 @default.
• W2599120840 cites W2101096291 @default.
• W2599120840 cites W2102164310 @default.
• W2599120840 cites W2102239053 @default.
• W2599120840 cites W2103503454 @default.
• W2599120840 cites W2105618126 @default.
• W2599120840 cites W2109719123 @default.
• W2599120840 cites W2113273019 @default.
• W2599120840 cites W2113420364 @default.
• W2599120840 cites W2114434059 @default.
• W2599120840 cites W2116527093 @default.
• W2599120840 cites W2123645680 @default.
• W2599120840 cites W2124445891 @default.
• W2599120840 cites W2125265960 @default.
• W2599120840 cites W2125416034 @default.
• W2599120840 cites W2130201635 @default.
• W2599120840 cites W2130599662 @default.
• W2599120840 cites W2132057657 @default.
• W2599120840 cites W2135696727 @default.
• W2599120840 cites W2135737750 @default.
• W2599120840 cites W2136327827 @default.
• W2599120840 cites W2145792008 @default.
• W2599120840 cites W2146429915 @default.
• W2599120840 cites W2150715314 @default.
• W2599120840 cites W2151783974 @default.
• W2599120840 cites W2152347367 @default.
• W2599120840 cites W2154171253 @default.
• W2599120840 cites W2157046025 @default.
• W2599120840 cites W2159574871 @default.
• W2599120840 cites W2159705293 @default.
• W2599120840 cites W2160765784 @default.
• W2599120840 cites W2164908048 @default.
• W2599120840 cites W2165490685 @default.
• W2599120840 cites W2165793295 @default.
• W2599120840 cites W2171331783 @default.
• W2599120840 cites W2171511525 @default.

• next