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- W2599156540 abstract "Highly stereoselective solid-phase asymmetric alkylation reactions were achieved by using Evans-type oxazolidinone 1 as a chiral auxiliary. Benzylation at the α-position of propionic acid (R1 = CH3) gave 2-methyl-3-phenylpropionic acid in 70% yield with 97% ee in three steps. The resin-supported chiral auxiliary 1 was recovered by simple filtration and was reused three times without any loss of stereoselectivity (1st to 4th 96% ee, R1 = Bn, R2 = allyl)." @default.
- W2599156540 created "2017-04-07" @default.
- W2599156540 date "2005-07-20" @default.
- W2599156540 modified "2023-10-09" @default.
- W2599156540 title "Evans’ Asymmetric Alkylation on Solid Supports" @default.
- W2599156540 doi "https://doi.org/10.1055/s-2005-869888" @default.
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