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• W2599376363 abstract "Background Chronic intestinal idiopathic pseudo-obstruction (idiopathic CIPO) is a rare heterogeneous condition for which the different phenotypes are difficult to be established. Oesophageal motility has shown to be impaired in patients with idiopathic CIPO at traditional manometry, whereas no studies have assessed it by high resolution manometry (HRM). Aims To evaluate oesophageal motility by HRM in patients with idiopathic CIPO. Methods 14 patients with idiopathic CIPO underwent oesophageal HRM. Multiple rapid swallows (MRS) were performed in order to evaluate contraction reserve. The Chicago Classification 3.0 was used to classify the oesophageal motility disorders. Results One idiopathic CIPO patient had type-II achalasia, one aperistalsis and 12 had minor disorder of peristalsis (11 ineffective oesophageal motility and one fragmented peristalsis). These minor disorders were not significantly different from those of 50 other consecutive patients who underwent HRM for dysphagia or GERD and received the diagnosis of ineffective oesophageal motility. Three of the 12 idiopathic CIPO patients with minor disorder of peristalsis had no contraction reserve after MRS. Conclusions HRM is able to identify different grades of oesophageal motor impairment in patients with idiopathic CIPO. Presence of major oesophageal dismotility or absent contraction reserve suggest a more severe and widespread motor disorder." @default.
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• W2599376363 date "2018-02-01" @default.
• W2599376363 modified "2023-10-14" @default.
• W2599376363 title "Oesophageal motor function in chronic intestinal idiopathic pseudo-obstruction: A study with high-resolution manometry" @default.
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• W2599376363 doi "https://doi.org/10.1016/j.dld.2017.10.008" @default.
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