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- W2599697084 abstract "Pain is prevalent in head and neck cancer. Studies indicate that up to 70% of patients will experience pain after diagnosis. Functional impairment resulting from head and neck cancer and its treatment is also prevalent. Studies show that between 17% and 59% of patients may discontinue work after cancer treatment. However, the impact of pain on function from head and neck cancer and its treatment remains unclear. We conducted a systematic literature review to examine the impact of symptoms on function in head and neck cancer. Using CINAHL, PsycINFO, PubMed, and Health and Psychosocial Instruments (HaPI) databases, the search generated 241 candidate articles. Two independent researchers examined these 241 articles for clinical studies that included symptom and function assessment questionnaires used in head and neck cancer. Ultimately, 32 articles were selected for review. In these articles, pain was most frequently measured by the Functional Assessment of Cancer Therapy – Head and Neck (31%, 10 of 32 articles) and the EORTC QLQ-C30 (19%, 6 of 32 articles) . Patients reported pain at differing sites, including neck and shoulder, that potentially impacted their lives up to five years after diagnosis. Interventions that significantly controlled pain or improved function were structured exercise regimens and oral pain medications. Study limitations included small populations and lack of clarity between symptom and function concepts. In conclusion, this literature review indicates an important association between pain and function in head and neck cancer. Large clinical trials are needed to test promising exercise and pharmacologic interventions. However, the limitations of current literature suggests the need for future research to clarify the concepts of symptoms and function in head and neck cancer. This work was supported by grants from the John A. Hartford Foundation and NYU University Research Challenge Fund." @default.
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- W2599697084 date "2017-04-01" @default.
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- W2599697084 title "(434) Pain and function in head and neck cancer: a systematic literature review" @default.
- W2599697084 doi "https://doi.org/10.1016/j.jpain.2017.02.284" @default.
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