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- W2599763765 abstract "Cool ambient temperatures are major cues determining flowering time in spring. The mechanisms promoting or delaying flowering in response to ambient temperature changes are only beginning to be understood. In Arabidopsis thaliana, FLOWERING LOCUS M (FLM) regulates flowering in the ambient temperature range and FLM is transcribed and alternatively spliced in a temperature-dependent manner. We identify polymorphic promoter and intronic sequences required for FLM expression and splicing. In transgenic experiments covering 69% of the available sequence variation in two distinct sites, we show that variation in the abundance of the FLM-ß splice form strictly correlate (R2 = 0.94) with flowering time over an extended vegetative period. The FLM polymorphisms lead to changes in FLM expression (PRO2+) but may also affect FLM intron 1 splicing (INT6+). This information could serve to buffer the anticipated negative effects on agricultural systems and flowering that may occur during climate change." @default.
- W2599763765 created "2017-04-07" @default.
- W2599763765 creator A5039331758 @default.
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- W2599763765 date "2017-03-15" @default.
- W2599763765 modified "2023-10-18" @default.
- W2599763765 title "Natural haplotypes of FLM non-coding sequences fine-tune flowering time in ambient spring temperatures in Arabidopsis" @default.
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- W2599763765 doi "https://doi.org/10.7554/elife.22114" @default.
- W2599763765 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5388537" @default.
- W2599763765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28294941" @default.
- W2599763765 hasPublicationYear "2017" @default.
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