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• W2599850502 abstract "Perfusion MRI, specifically dynamic susceptibility MRI (DSC-MRI) is routinely performed as a supplement to conventional MRI in human medicine for patients with intra-cranial neoplasia and cerebrovascular events. There is minimal data on the use of DSC-MRI in veterinary patients and a DSC-MRI protocol in the veterinary patient has not been described. Sixteen normal dogs, 6 years or older were recruited for this study. The sample population included 11 large dogs (>11kg) and 5 small dogs (11kg, a useable arterial input function (AIF) and perfusion map was generated. One dog less than 11kg received the same contrast dose and rate. In this patient, the protocol did not generate a useable AIF. The remainder of the dogs less than 11kg followed a protocol of 0.2mmol/kg gadolinium-based contrast media at 1.5ml/sec with a 10ml saline flush at 1.5 ml/sec. A useable AIF and perfusion map was generated in the remaining dogs <11kg using the higher contrast dose and slower rate protocol. This study establishes a contrast dose and administration rate for canine DSC-MRI imaging that is different in dogs greater than 11kg compared to dogs less than 11kg. These protocols may be used for future applications to evaluate hemodynamic disturbances in canine intracranial pathology." @default.
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• W2599850502 date "2017-03-21" @default.
• W2599850502 modified "2023-09-27" @default.
• W2599850502 title "Dynamic Susceptibility Contrast Magnetic Resonance Imaging Protocol of the Normal Canine Brain" @default.
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• W2599850502 doi "https://doi.org/10.3389/fvets.2017.00041" @default.
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