Matches in SemOpenAlex for { <https://semopenalex.org/work/W2599941868> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2599941868 endingPage "3" @default.
- W2599941868 startingPage "3" @default.
- W2599941868 abstract "Submacular haemorrhage (SMH) is a sight threatening complication that can occur in exudative age related macular degeneration (AMD), but has been described to occur more frequently in eyes with polypoidal choroidal vasculopathy (PCV). Left untreated, SMH carries a grave visual prognosis. Thus, expedient diagnosis and effective management of this complication is of paramount importance. The treatment strategies for SMH include (I) displacement of blood from the fovea, usually by injection of an expansile gas; (II) pharmacologic clot lysis such as with recombinant tissue plasminogen activator (rtPA); and (III) treatment of the underlying choroidal neovascularization (CNV) or PCV, such as with anti-vascular endothelial growth factor (anti-VEGF) agents. These three strategies have been employed in isolation or in combination, some concurrently and others in stages. rtPA has demonstrable effect on the liquefaction of submacular clots but there are remaining uncertainties with regards to the dose, safety and the timing of initial and repeat treatments. Potential side effects of rtPA include retinal pigment epithelial toxicity, increased risk of breakthrough vitreous haemorrhage and systemic toxicity. In cases presenting early, pneumatic displacement alone with anti-VEGF may be sufficient. Anti-VEGF monotherapy is a viable treatment option particularly in patients with thinner SMH and those who are unable to posture post pneumatic displacement." @default.
- W2599941868 created "2017-04-07" @default.
- W2599941868 creator A5010283393 @default.
- W2599941868 creator A5047341719 @default.
- W2599941868 creator A5051514193 @default.
- W2599941868 creator A5078957389 @default.
- W2599941868 date "2018-01-01" @default.
- W2599941868 modified "2023-09-26" @default.
- W2599941868 title "Submacular hemorrhage: treatment update and remaining challenges" @default.
- W2599941868 doi "https://doi.org/10.21037/aes.2016.12.06" @default.
- W2599941868 hasPublicationYear "2018" @default.
- W2599941868 type Work @default.
- W2599941868 sameAs 2599941868 @default.
- W2599941868 citedByCount "1" @default.
- W2599941868 countsByYear W25999418682020 @default.
- W2599941868 crossrefType "journal-article" @default.
- W2599941868 hasAuthorship W2599941868A5010283393 @default.
- W2599941868 hasAuthorship W2599941868A5047341719 @default.
- W2599941868 hasAuthorship W2599941868A5051514193 @default.
- W2599941868 hasAuthorship W2599941868A5078957389 @default.
- W2599941868 hasConcept C118487528 @default.
- W2599941868 hasConcept C126322002 @default.
- W2599941868 hasConcept C141071460 @default.
- W2599941868 hasConcept C2776403814 @default.
- W2599941868 hasConcept C2776572282 @default.
- W2599941868 hasConcept C2776694085 @default.
- W2599941868 hasConcept C2777802072 @default.
- W2599941868 hasConcept C2778271429 @default.
- W2599941868 hasConcept C2780394083 @default.
- W2599941868 hasConcept C2780827179 @default.
- W2599941868 hasConcept C2780931571 @default.
- W2599941868 hasConcept C2781100027 @default.
- W2599941868 hasConcept C2781359195 @default.
- W2599941868 hasConcept C2911092318 @default.
- W2599941868 hasConcept C29730261 @default.
- W2599941868 hasConcept C3020199598 @default.
- W2599941868 hasConcept C541997718 @default.
- W2599941868 hasConcept C71924100 @default.
- W2599941868 hasConcept C81182388 @default.
- W2599941868 hasConceptScore W2599941868C118487528 @default.
- W2599941868 hasConceptScore W2599941868C126322002 @default.
- W2599941868 hasConceptScore W2599941868C141071460 @default.
- W2599941868 hasConceptScore W2599941868C2776403814 @default.
- W2599941868 hasConceptScore W2599941868C2776572282 @default.
- W2599941868 hasConceptScore W2599941868C2776694085 @default.
- W2599941868 hasConceptScore W2599941868C2777802072 @default.
- W2599941868 hasConceptScore W2599941868C2778271429 @default.
- W2599941868 hasConceptScore W2599941868C2780394083 @default.
- W2599941868 hasConceptScore W2599941868C2780827179 @default.
- W2599941868 hasConceptScore W2599941868C2780931571 @default.
- W2599941868 hasConceptScore W2599941868C2781100027 @default.
- W2599941868 hasConceptScore W2599941868C2781359195 @default.
- W2599941868 hasConceptScore W2599941868C2911092318 @default.
- W2599941868 hasConceptScore W2599941868C29730261 @default.
- W2599941868 hasConceptScore W2599941868C3020199598 @default.
- W2599941868 hasConceptScore W2599941868C541997718 @default.
- W2599941868 hasConceptScore W2599941868C71924100 @default.
- W2599941868 hasConceptScore W2599941868C81182388 @default.
- W2599941868 hasLocation W25999418681 @default.
- W2599941868 hasOpenAccess W2599941868 @default.
- W2599941868 hasPrimaryLocation W25999418681 @default.
- W2599941868 hasRelatedWork W1987475363 @default.
- W2599941868 hasRelatedWork W2024548441 @default.
- W2599941868 hasRelatedWork W2070237388 @default.
- W2599941868 hasRelatedWork W2233259956 @default.
- W2599941868 hasRelatedWork W2396116581 @default.
- W2599941868 hasRelatedWork W2682124582 @default.
- W2599941868 hasRelatedWork W2760097671 @default.
- W2599941868 hasRelatedWork W766415076 @default.
- W2599941868 hasRelatedWork W903538081 @default.
- W2599941868 hasRelatedWork W2599281049 @default.
- W2599941868 hasVolume "2" @default.
- W2599941868 isParatext "false" @default.
- W2599941868 isRetracted "false" @default.
- W2599941868 magId "2599941868" @default.
- W2599941868 workType "article" @default.