FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2599972009> ?p ?o ?g. }

• W2599972009 endingPage "63" @default.
• W2599972009 startingPage "57" @default.
• W2599972009 abstract "Although epidural analgesia is considered the gold standard for labor pain management, its use may be restricted in some conditions due to clinical contraindications or availability, and suitable alternatives may be required. The objective of this meta-analysis was to determine whether evidence from randomized trials suggests remifentanil PCA (R-PCA) results in significant differences in maternal satisfaction, analgesic efficacy, and safety compared with conventional epidural analgesia (EA). We conducted a meta-analysis after systematically searching MEDLINE, EMBASE and Cochrane Library for all randomized controlled trials (RCTs) allocating parturients to R-PCA or EA and reporting at least one outcome of interest. Eight randomized trials of R-PCA vs EA with 2351 patients were included. The primary outcome of interest was maternal satisfaction. Secondary outcomes included visual analog pain score (VAS at 1, 2, 3 h postoperatively), nausea, vomiting, pruritus, hypoxemia, acute respiratory depression or death (maternal or neonatal), need for Cesarean section, and neonatal Apgar score. Meta-analysis of the randomized trials showed no significant differences between the R-PCA and EA groups for maternal satisfaction, VAS at 2 or 3 h, nausea, vomiting, need for cesarean section, respiratory depression, umbilical pH, and neonatal Apgar score at 1 min and 5 min. However, incidence of hypoxemia was higher [OR 7.48, 95%CI 3.42–16.36] and VAS at 1 h was slightly higher [WMD 1.33, 95%CI 0.30–2.36] with R-PCA versus EA. Pruritus was less frequent in the R-PCA group [OR 0.54, 95%CI 0.32–0.89]. Acute respiratory failure and death were not reported in any of the studies. While no significant differences were detected for maternal satisfaction or for most clinical outcomes, this meta-analysis remains underpowered to rule out clinically-important differences due to the few existing randomized trials. For obstetric patients who are not candidates for EA, R-PCA may provide an alternative for analgesia in the peri-partum period, but caution is warranted particularly regarding hypoxemia, and suggests the need for increased surveillance and monitoring for R-PCA. Further adequately powered randomized trials with a focus on clinically-relevant maternal and neonatal outcomes are required to more accurately characterize the relative benefits and risks of R-PCA versus EA in this population." @default.
• W2599972009 created "2017-04-07" @default.
• W2599972009 creator A5008526274 @default.
• W2599972009 creator A5023283658 @default.
• W2599972009 creator A5030611586 @default.
• W2599972009 creator A5046694154 @default.
• W2599972009 creator A5077558876 @default.
• W2599972009 creator A5085766566 @default.
• W2599972009 date "2017-06-01" @default.
• W2599972009 modified "2023-09-25" @default.
• W2599972009 title "Remifentanil as an alternative to epidural analgesia for vaginal delivery: A meta-analysis of randomized trials" @default.
• W2599972009 cites W1506297997 @default.
• W2599972009 cites W1965879639 @default.
• W2599972009 cites W1977048484 @default.
• W2599972009 cites W1982460292 @default.
• W2599972009 cites W1986215651 @default.
• W2599972009 cites W1986801308 @default.
• W2599972009 cites W1988522868 @default.
• W2599972009 cites W1995586345 @default.
• W2599972009 cites W2007679432 @default.
• W2599972009 cites W2034888339 @default.
• W2599972009 cites W2066376782 @default.
• W2599972009 cites W2068293404 @default.
• W2599972009 cites W2070639513 @default.
• W2599972009 cites W2097879855 @default.
• W2599972009 cites W2100426868 @default.
• W2599972009 cites W2103858265 @default.
• W2599972009 cites W2122614564 @default.
• W2599972009 cites W2149583225 @default.
• W2599972009 cites W2158248418 @default.
• W2599972009 cites W2204984085 @default.
• W2599972009 cites W2211255301 @default.
• W2599972009 cites W2314996752 @default.
• W2599972009 cites W2335699532 @default.
• W2599972009 cites W2576440140 @default.
• W2599972009 cites W2914684004 @default.
• W2599972009 cites W4250327949 @default.
• W2599972009 cites W4362115503 @default.
• W2599972009 doi "https://doi.org/10.1016/j.jclinane.2017.03.026" @default.
• W2599972009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28494909" @default.
• W2599972009 hasPublicationYear "2017" @default.
• W2599972009 type Work @default.
• W2599972009 sameAs 2599972009 @default.
• W2599972009 citedByCount "24" @default.
• W2599972009 countsByYear W25999720092017 @default.
• W2599972009 countsByYear W25999720092018 @default.
• W2599972009 countsByYear W25999720092019 @default.
• W2599972009 countsByYear W25999720092020 @default.
• W2599972009 countsByYear W25999720092021 @default.
• W2599972009 countsByYear W25999720092022 @default.
• W2599972009 countsByYear W25999720092023 @default.
• W2599972009 crossrefType "journal-article" @default.
• W2599972009 hasAuthorship W2599972009A5008526274 @default.
• W2599972009 hasAuthorship W2599972009A5023283658 @default.
• W2599972009 hasAuthorship W2599972009A5030611586 @default.
• W2599972009 hasAuthorship W2599972009A5046694154 @default.
• W2599972009 hasAuthorship W2599972009A5077558876 @default.
• W2599972009 hasAuthorship W2599972009A5085766566 @default.
• W2599972009 hasConcept C126322002 @default.
• W2599972009 hasConcept C141071460 @default.
• W2599972009 hasConcept C168563851 @default.
• W2599972009 hasConcept C2776277131 @default.
• W2599972009 hasConcept C2778052368 @default.
• W2599972009 hasConcept C2778376644 @default.
• W2599972009 hasConcept C2778891214 @default.
• W2599972009 hasConcept C2779234561 @default.
• W2599972009 hasConcept C2780580376 @default.
• W2599972009 hasConcept C2780820201 @default.
• W2599972009 hasConcept C2780852908 @default.
• W2599972009 hasConcept C42219234 @default.
• W2599972009 hasConcept C54355233 @default.
• W2599972009 hasConcept C71924100 @default.
• W2599972009 hasConcept C86803240 @default.
• W2599972009 hasConcept C95190672 @default.
• W2599972009 hasConceptScore W2599972009C126322002 @default.
• W2599972009 hasConceptScore W2599972009C141071460 @default.
• W2599972009 hasConceptScore W2599972009C168563851 @default.
• W2599972009 hasConceptScore W2599972009C2776277131 @default.
• W2599972009 hasConceptScore W2599972009C2778052368 @default.
• W2599972009 hasConceptScore W2599972009C2778376644 @default.
• W2599972009 hasConceptScore W2599972009C2778891214 @default.
• W2599972009 hasConceptScore W2599972009C2779234561 @default.
• W2599972009 hasConceptScore W2599972009C2780580376 @default.
• W2599972009 hasConceptScore W2599972009C2780820201 @default.
• W2599972009 hasConceptScore W2599972009C2780852908 @default.
• W2599972009 hasConceptScore W2599972009C42219234 @default.
• W2599972009 hasConceptScore W2599972009C54355233 @default.
• W2599972009 hasConceptScore W2599972009C71924100 @default.
• W2599972009 hasConceptScore W2599972009C86803240 @default.
• W2599972009 hasConceptScore W2599972009C95190672 @default.
• W2599972009 hasFunder F4320321372 @default.
• W2599972009 hasLocation W25999720091 @default.
• W2599972009 hasLocation W25999720092 @default.
• W2599972009 hasOpenAccess W2599972009 @default.
• W2599972009 hasPrimaryLocation W25999720091 @default.
• W2599972009 hasRelatedWork W2117435351 @default.
• W2599972009 hasRelatedWork W2352349240 @default.
• W2599972009 hasRelatedWork W2362111834 @default.

• next