FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2600118519> ?p ?o ?g. }

• W2600118519 endingPage "545" @default.
• W2600118519 startingPage "533" @default.
• W2600118519 abstract "The purpose of this article was to inform the first-line treatment choice between cognitive-behavioral therapy (CBT) or an antidepressant medication for treatment-naive adults with major depressive disorder by defining a neuroimaging biomarker that differentially identifies the outcomes of remission and treatment failure to these interventions.Functional MRI resting-state functional connectivity analyses using a bilateral subcallosal cingulate cortex (SCC) seed was applied to 122 patients from the Prediction of Remission to Individual and Combined Treatments (PReDICT) study who completed 12 weeks of randomized treatment with CBT or antidepressant medication. Of the 122 participants, 58 achieved remission (Hamilton Depression Rating Scale [HAM-D] score ≤7 at weeks 10 and 12), and 24 had treatment failure (<30% decrease from baseline in HAM-D score). A 2×2 analysis of variance using voxel-wise subsampling permutation tests compared the interaction of treatment and outcome. Receiver operating characteristic curves constructed using brain connectivity measures were used to determine possible classification rates for differential treatment outcomes.The resting-state functional connectivity of the following three regions with the SCC was differentially associated with outcomes of remission and treatment failure to CBT and antidepressant medication and survived application of the subsample permutation tests: the left anterior ventrolateral prefrontal cortex/insula, the dorsal midbrain, and the left ventromedial prefrontal cortex. Using the summed SCC functional connectivity scores for these three regions, overall classification rates of 72%-78% for remission and 75%-89% for treatment failure was demonstrated. Positive summed functional connectivity was associated with remission with CBT and treatment failure with medication, whereas negative summed functional connectivity scores were associated with remission to medication and treatment failure with CBT.Imaging-based depression subtypes defined using resting-state functional connectivity differentially identified an individual's probability of remission or treatment failure with first-line treatment options for major depression. This biomarker should be explored in future research through prospective testing and as a component of multivariate treatment prediction models." @default.
• W2600118519 created "2017-04-07" @default.
• W2600118519 creator A5026199142 @default.
• W2600118519 creator A5030041634 @default.
• W2600118519 creator A5037210460 @default.
• W2600118519 creator A5056637382 @default.
• W2600118519 creator A5056708300 @default.
• W2600118519 creator A5065816117 @default.
• W2600118519 creator A5077446875 @default.
• W2600118519 creator A5078348766 @default.
• W2600118519 creator A5081120570 @default.
• W2600118519 date "2017-06-01" @default.
• W2600118519 modified "2023-10-10" @default.
• W2600118519 title "Functional Connectivity of the Subcallosal Cingulate Cortex And Differential Outcomes to Treatment With Cognitive-Behavioral Therapy or Antidepressant Medication for Major Depressive Disorder" @default.
• W2600118519 cites W1536164666 @default.
• W2600118519 cites W1538313140 @default.
• W2600118519 cites W1670869140 @default.
• W2600118519 cites W1760829075 @default.
• W2600118519 cites W1763310011 @default.
• W2600118519 cites W1813695827 @default.
• W2600118519 cites W1858671351 @default.
• W2600118519 cites W1969152719 @default.
• W2600118519 cites W1970006078 @default.
• W2600118519 cites W1973854788 @default.
• W2600118519 cites W1975345989 @default.
• W2600118519 cites W1976073163 @default.
• W2600118519 cites W1979650623 @default.
• W2600118519 cites W1990134753 @default.
• W2600118519 cites W1993273089 @default.
• W2600118519 cites W1993623582 @default.
• W2600118519 cites W1999520265 @default.
• W2600118519 cites W1999682854 @default.
• W2600118519 cites W2001249543 @default.
• W2600118519 cites W2002611894 @default.
• W2600118519 cites W2009268976 @default.
• W2600118519 cites W2012691107 @default.
• W2600118519 cites W202043522 @default.
• W2600118519 cites W2020677557 @default.
• W2600118519 cites W2026088841 @default.
• W2600118519 cites W2037037154 @default.
• W2600118519 cites W2042404539 @default.
• W2600118519 cites W2046140176 @default.
• W2600118519 cites W2048593992 @default.
• W2600118519 cites W2049423401 @default.
• W2600118519 cites W2055267098 @default.
• W2600118519 cites W2060427373 @default.
• W2600118519 cites W2063122336 @default.
• W2600118519 cites W2067495470 @default.
• W2600118519 cites W2072296702 @default.
• W2600118519 cites W2073690998 @default.
• W2600118519 cites W2082471440 @default.
• W2600118519 cites W2084297734 @default.
• W2600118519 cites W2084335923 @default.
• W2600118519 cites W2090687144 @default.
• W2600118519 cites W2095438393 @default.
• W2600118519 cites W2096937559 @default.
• W2600118519 cites W2098818989 @default.
• W2600118519 cites W2100991928 @default.
• W2600118519 cites W2101135654 @default.
• W2600118519 cites W2107790366 @default.
• W2600118519 cites W2111456519 @default.
• W2600118519 cites W2114613490 @default.
• W2600118519 cites W2123600659 @default.
• W2600118519 cites W2126437271 @default.
• W2600118519 cites W2128667519 @default.
• W2600118519 cites W2129028793 @default.
• W2600118519 cites W2130136912 @default.
• W2600118519 cites W2133371501 @default.
• W2600118519 cites W2138538218 @default.
• W2600118519 cites W2140592967 @default.
• W2600118519 cites W2144538553 @default.
• W2600118519 cites W2145702255 @default.
• W2600118519 cites W2147969224 @default.
• W2600118519 cites W2148011447 @default.
• W2600118519 cites W2152575748 @default.
• W2600118519 cites W2157607979 @default.
• W2600118519 cites W2160070901 @default.
• W2600118519 cites W2160609978 @default.
• W2600118519 cites W2162056840 @default.
• W2600118519 cites W2169186415 @default.
• W2600118519 cites W2170955297 @default.
• W2600118519 cites W2175558603 @default.
• W2600118519 cites W2184999462 @default.
• W2600118519 cites W2260776258 @default.
• W2600118519 cites W2341692630 @default.
• W2600118519 cites W2559866074 @default.
• W2600118519 cites W2601834048 @default.
• W2600118519 cites W2737966001 @default.
• W2600118519 cites W2777987555 @default.
• W2600118519 cites W319710766 @default.
• W2600118519 cites W4250233253 @default.
• W2600118519 doi "https://doi.org/10.1176/appi.ajp.2016.16050518" @default.
• W2600118519 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5453828" @default.
• W2600118519 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28335622" @default.
• W2600118519 hasPublicationYear "2017" @default.
• W2600118519 type Work @default.
• W2600118519 sameAs 2600118519 @default.
• W2600118519 citedByCount "229" @default.

• next