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• W2600353090 endingPage "2016" @default.
• W2600353090 startingPage "00135" @default.
• W2600353090 abstract "The aim of the present study was to determine whether lung volume recruitment (LVR) acutely increases respiratory system compliance ( C rs ) in individuals with severe respiratory muscle weakness (RMW). Individuals with RMW resulting from neuromuscular disease or quadriplegia (n=12) and healthy controls (n=12) underwent pulmonary function testing and the measurement of C rs at baseline, immediately after, 1 h after and 2 h after a single standardised session of LVR. The LVR session involved 10 consecutive supramaximal lung inflations with a manual resuscitation bag to the highest tolerable mouth pressure or a maximum of 50 cmH 2 O. Each LVR inflation was followed by brief breath-hold and a maximal expiration to residual volume. At baseline, individuals with RMW had lower C rs than controls (37±5 cmH 2 O versus 109±10 mL·cmH 2 O −1 , p<0.001). Immediately after LVR, C rs increased by 39.5±9.8% to 50±7 mL·cmH 2 O −1 in individuals with RMW (p<0.05), while no significant change occurred in controls (p=0.23). At 1 h and 2 h post-treatment, there were no within-group differences in C rs compared to baseline (all p>0.05). LVR had no significant effect on measures of pulmonary function at any time point in either group (all p>0.05). During inflations, mean arterial pressure decreased significantly relative to baseline by 10.4±2.8 mmHg and 17.3±3.0 mmHg in individuals with RMW and controls, respectively (both p<0.05). LVR acutely increases C rs in individuals with RMW. However, the high airway pressures during inflations cause reductions in mean arterial pressure that should be considered when applying this technique." @default.
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• W2600353090 date "2017-01-01" @default.
• W2600353090 modified "2023-10-11" @default.
• W2600353090 title "Lung volume recruitment acutely increases respiratory system compliance in individuals with severe respiratory muscle weakness" @default.
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• W2600353090 doi "https://doi.org/10.1183/23120541.00135-2016" @default.
• W2600353090 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5349097" @default.
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