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- W2600372788 abstract "To compare the relationship between Ktrans from DCE-MRI and K1 from dynamic 13N-NH3-PET, with simultaneous and separate MR/PET in the VX-2 rabbit carcinoma model.MR/PET was performed simultaneously and separately, 14 and 15 days after VX-2 tumor implantation at the paravertebral muscle. The Ktrans and K1 values were estimated using an in-house software program. The relationships between Ktrans and K1 were analyzed using Pearson's correlation coefficients and linear/non-linear regression function.Assuming a linear relationship, Ktrans and K1 exhibited a moderate positive correlations with both simultaneous (r=0.54-0.57) and separate (r=0.53-0.69) imaging. However, while the Ktrans and K1 from separate imaging were linearly correlated, those from simultaneous imaging exhibited a non-linear relationship. The amount of change in K1 associated with a unit increase in Ktrans varied depending on Ktrans values.The relationship between Ktrans and K1 may be mis-interpreted with separate MR and PET acquisition." @default.
- W2600372788 created "2017-04-07" @default.
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- W2600372788 date "2017-03-17" @default.
- W2600372788 modified "2023-09-23" @default.
- W2600372788 title "Relationship Between Ktrans and K1 with Simultaneous Versus Separate MR/PET in Rabbits with VX2 Tumors" @default.
- W2600372788 doi "https://doi.org/10.21873/anticanres.11427" @default.
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