Matches in SemOpenAlex for { <https://semopenalex.org/work/W2600552647> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2600552647 endingPage "308" @default.
- W2600552647 startingPage "301" @default.
- W2600552647 abstract "化粧品製剤の重要な役割の一つに，有用素材を皮膚内へ運ぶことが挙げられる。皮膚には，外界からの異物の侵入を防いだり体内からの過剰な水分蒸散を防いだりする角層という強固なバリアが備わっているため，これまでの製剤技術開発者は，皮膚上に塗布した有用素材を角層より下の細胞に届けることに注力し，成果を上げてきた。したがって，開発された製剤技術の多くが角層への浸透性向上に対するアプローチであり，その下の表皮生細胞層での拡散浸透性はほとんど検討されてこなかった。われわれは角層とその下の表皮生細胞層で水分量が大きく異なることに着目し，両者に対する製剤の浸透性は異なるのではないかと仮説をたて，各々の層に分けて両親媒性物質会合体の浸透性を評価した。その結果，仮説どおり同一の製剤でも角層とその下の表皮生細胞層とでは浸透性が異なることが明らかとなり，角層と比較してこれまであまり着目されなかった表皮生細胞層に対する浸透性も，角層と同様に表皮全層の浸透性に大きく寄与していることが示唆された。すなわち，有用素材を目的の表皮細胞まで効率的に運ぶには，角層に加えて表皮生細胞層に対する浸透性も考慮することが重要であると考えた。" @default.
- W2600552647 created "2017-04-07" @default.
- W2600552647 creator A5004233970 @default.
- W2600552647 creator A5012339019 @default.
- W2600552647 creator A5031050138 @default.
- W2600552647 creator A5088730034 @default.
- W2600552647 date "2015-01-01" @default.
- W2600552647 modified "2023-10-05" @default.
- W2600552647 title "A Proposal for a Permeation Strategy for Cosmetic Preparations Using Self-assemblies of Amphiphiles, Considering Heterogeneity in the Multi-layered Epidermis" @default.
- W2600552647 cites W1578743166 @default.
- W2600552647 cites W1967215291 @default.
- W2600552647 cites W1984929230 @default.
- W2600552647 cites W1996823721 @default.
- W2600552647 cites W2000966264 @default.
- W2600552647 cites W2034011432 @default.
- W2600552647 cites W2034533820 @default.
- W2600552647 cites W2049843789 @default.
- W2600552647 cites W2074937552 @default.
- W2600552647 cites W2075087590 @default.
- W2600552647 cites W2081578825 @default.
- W2600552647 cites W2094415452 @default.
- W2600552647 cites W2095785632 @default.
- W2600552647 cites W2137902073 @default.
- W2600552647 cites W2138980875 @default.
- W2600552647 cites W2970291492 @default.
- W2600552647 doi "https://doi.org/10.5107/sccj.49.301" @default.
- W2600552647 hasPublicationYear "2015" @default.
- W2600552647 type Work @default.
- W2600552647 sameAs 2600552647 @default.
- W2600552647 citedByCount "0" @default.
- W2600552647 crossrefType "journal-article" @default.
- W2600552647 hasAuthorship W2600552647A5004233970 @default.
- W2600552647 hasAuthorship W2600552647A5012339019 @default.
- W2600552647 hasAuthorship W2600552647A5031050138 @default.
- W2600552647 hasAuthorship W2600552647A5088730034 @default.
- W2600552647 hasBestOaLocation W26005526471 @default.
- W2600552647 hasConcept C105702510 @default.
- W2600552647 hasConcept C126348684 @default.
- W2600552647 hasConcept C127413603 @default.
- W2600552647 hasConcept C15920480 @default.
- W2600552647 hasConcept C171250308 @default.
- W2600552647 hasConcept C178790620 @default.
- W2600552647 hasConcept C183696295 @default.
- W2600552647 hasConcept C185592680 @default.
- W2600552647 hasConcept C192562407 @default.
- W2600552647 hasConcept C2776458125 @default.
- W2600552647 hasConcept C41625074 @default.
- W2600552647 hasConcept C50670333 @default.
- W2600552647 hasConcept C521977710 @default.
- W2600552647 hasConcept C55493867 @default.
- W2600552647 hasConcept C67407626 @default.
- W2600552647 hasConcept C86803240 @default.
- W2600552647 hasConceptScore W2600552647C105702510 @default.
- W2600552647 hasConceptScore W2600552647C126348684 @default.
- W2600552647 hasConceptScore W2600552647C127413603 @default.
- W2600552647 hasConceptScore W2600552647C15920480 @default.
- W2600552647 hasConceptScore W2600552647C171250308 @default.
- W2600552647 hasConceptScore W2600552647C178790620 @default.
- W2600552647 hasConceptScore W2600552647C183696295 @default.
- W2600552647 hasConceptScore W2600552647C185592680 @default.
- W2600552647 hasConceptScore W2600552647C192562407 @default.
- W2600552647 hasConceptScore W2600552647C2776458125 @default.
- W2600552647 hasConceptScore W2600552647C41625074 @default.
- W2600552647 hasConceptScore W2600552647C50670333 @default.
- W2600552647 hasConceptScore W2600552647C521977710 @default.
- W2600552647 hasConceptScore W2600552647C55493867 @default.
- W2600552647 hasConceptScore W2600552647C67407626 @default.
- W2600552647 hasConceptScore W2600552647C86803240 @default.
- W2600552647 hasIssue "4" @default.
- W2600552647 hasLocation W26005526471 @default.
- W2600552647 hasOpenAccess W2600552647 @default.
- W2600552647 hasPrimaryLocation W26005526471 @default.
- W2600552647 hasRelatedWork W1973753037 @default.
- W2600552647 hasRelatedWork W1999426851 @default.
- W2600552647 hasRelatedWork W2011182618 @default.
- W2600552647 hasRelatedWork W2322389413 @default.
- W2600552647 hasRelatedWork W2547005920 @default.
- W2600552647 hasRelatedWork W2600552647 @default.
- W2600552647 hasRelatedWork W2899084033 @default.
- W2600552647 hasRelatedWork W2473760299 @default.
- W2600552647 hasRelatedWork W2486634905 @default.
- W2600552647 hasRelatedWork W2951415413 @default.
- W2600552647 hasVolume "49" @default.
- W2600552647 isParatext "false" @default.
- W2600552647 isRetracted "false" @default.
- W2600552647 magId "2600552647" @default.
- W2600552647 workType "article" @default.