FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2600656194> ?p ?o ?g. }

• W2600656194 endingPage "15" @default.
• W2600656194 startingPage "1" @default.
• W2600656194 abstract "The gut microbiota comprises a complex community of microorganism species that resides in our gastrointestinal ecosystem and whose alterations influence not only various gut disorders but also central nervous system disorders such as Alzheimer's disease (AD). AD, the most common form of dementia, is a neurodegenerative disorder associated with impaired cognition and cerebral accumulation of amyloid-β peptides (Aβ). Most notably, the microbiota-gut-brain axis is a bidirectional communication system that is not fully understood, but includes neural, immune, endocrine, and metabolic pathways. Studies in germ-free animals and in animals exposed to pathogenic microbial infections, antibiotics, probiotics, or fecal microbiota transplantation suggest a role for the gut microbiota in host cognition or AD-related pathogenesis. The increased permeability of the gut and blood-brain barrier induced by microbiota dysbiosis may mediate or affect AD pathogenesis and other neurodegenerative disorders, especially those associated with aging. In addition, bacteria populating the gut microbiota can secrete large amounts of amyloids and lipopolysaccharides, which might contribute to the modulation of signaling pathways and the production of proinflammatory cytokines associated with the pathogenesis of AD. Moreover, imbalances in the gut microbiota can induce inflammation that is associated with the pathogenesis of obesity, type 2 diabetes mellitus, and AD. The purpose of this review is to summarize and discuss the current findings that may elucidate the role of the gut microbiota in the development of AD. Understanding the underlying mechanisms may provide new insights into novel therapeutic strategies for AD." @default.
• W2600656194 created "2017-04-07" @default.
• W2600656194 creator A5026888948 @default.
• W2600656194 creator A5042968579 @default.
• W2600656194 creator A5055347404 @default.
• W2600656194 creator A5074590231 @default.
• W2600656194 creator A5084363913 @default.
• W2600656194 date "2017-05-03" @default.
• W2600656194 modified "2023-10-17" @default.
• W2600656194 title "The Gut Microbiota and Alzheimer’s Disease" @default.
• W2600656194 cites W1515023627 @default.
• W2600656194 cites W1526611045 @default.
• W2600656194 cites W157594748 @default.
• W2600656194 cites W1711618188 @default.
• W2600656194 cites W1841850981 @default.
• W2600656194 cites W1920510593 @default.
• W2600656194 cites W1934236512 @default.
• W2600656194 cites W1953255974 @default.
• W2600656194 cites W1970308163 @default.
• W2600656194 cites W1971415551 @default.
• W2600656194 cites W1974476511 @default.
• W2600656194 cites W1978686657 @default.
• W2600656194 cites W1979216870 @default.
• W2600656194 cites W1980914602 @default.
• W2600656194 cites W1981500982 @default.
• W2600656194 cites W1981801578 @default.
• W2600656194 cites W1982795519 @default.
• W2600656194 cites W1989565555 @default.
• W2600656194 cites W1990516887 @default.
• W2600656194 cites W1993623582 @default.
• W2600656194 cites W1995525413 @default.
• W2600656194 cites W2002797282 @default.
• W2600656194 cites W2006221795 @default.
• W2600656194 cites W2008431663 @default.
• W2600656194 cites W2010055058 @default.
• W2600656194 cites W2012925380 @default.
• W2600656194 cites W2013322269 @default.
• W2600656194 cites W2013769097 @default.
• W2600656194 cites W2019250366 @default.
• W2600656194 cites W2020284094 @default.
• W2600656194 cites W2022036412 @default.
• W2600656194 cites W2023040110 @default.
• W2600656194 cites W2023615726 @default.
• W2600656194 cites W2025399737 @default.
• W2600656194 cites W2026689451 @default.
• W2600656194 cites W2029736480 @default.
• W2600656194 cites W2031441917 @default.
• W2600656194 cites W2032684594 @default.
• W2600656194 cites W2034275438 @default.
• W2600656194 cites W2034300480 @default.
• W2600656194 cites W2034897558 @default.
• W2600656194 cites W2036420702 @default.
• W2600656194 cites W2037907937 @default.
• W2600656194 cites W2043981492 @default.
• W2600656194 cites W2044842166 @default.
• W2600656194 cites W2046563865 @default.
• W2600656194 cites W2047798386 @default.
• W2600656194 cites W2048371740 @default.
• W2600656194 cites W2048887584 @default.
• W2600656194 cites W2049329367 @default.
• W2600656194 cites W2051765035 @default.
• W2600656194 cites W2052179757 @default.
• W2600656194 cites W2058473463 @default.
• W2600656194 cites W2061387301 @default.
• W2600656194 cites W2068910733 @default.
• W2600656194 cites W2071841602 @default.
• W2600656194 cites W2073332363 @default.
• W2600656194 cites W2074647381 @default.
• W2600656194 cites W2082402714 @default.
• W2600656194 cites W2082704291 @default.
• W2600656194 cites W2085818382 @default.
• W2600656194 cites W2087055632 @default.
• W2600656194 cites W2087084954 @default.
• W2600656194 cites W2087669636 @default.
• W2600656194 cites W2088170171 @default.
• W2600656194 cites W2088679551 @default.
• W2600656194 cites W2091319478 @default.
• W2600656194 cites W2097937398 @default.
• W2600656194 cites W2099448948 @default.
• W2600656194 cites W2099514643 @default.
• W2600656194 cites W2100011299 @default.
• W2600656194 cites W2104566435 @default.
• W2600656194 cites W2105229256 @default.
• W2600656194 cites W2109832621 @default.
• W2600656194 cites W2111574450 @default.
• W2600656194 cites W2112320675 @default.
• W2600656194 cites W2112681005 @default.
• W2600656194 cites W2113822705 @default.
• W2600656194 cites W2113944963 @default.
• W2600656194 cites W2115779804 @default.
• W2600656194 cites W2116802655 @default.
• W2600656194 cites W2122827512 @default.
• W2600656194 cites W2124334639 @default.
• W2600656194 cites W2124490243 @default.
• W2600656194 cites W2124896583 @default.
• W2600656194 cites W2125793671 @default.
• W2600656194 cites W2125826054 @default.
• W2600656194 cites W2127230663 @default.

• next