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- W2600705325 abstract "Background: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human malignan- cies with a mean survival time of 6 months regardless of treatment. Aim: To present a case of lo- cally advanced anaplastic thyroid carcinoma with long-term survival. A 10-year literature review of locally advanced ATC with long-term survival (more than 2 years) is also presented. Case pres- entation: We present a case of locally advanced anaplastic thyroid carcinoma (ATC) with tracheal invasion in a 67-year-old elderly Chinese man who was treated with radical surgery encompassing total thyroidectomy, neck dissection and tracheal resection followed by adjuvant radiotherapy. Long-term disease-free survival is more than 7 years to date. Conclusion: The prognosis of ATC remains poor as it is characterized by aggressive and extensive disease at presentation, the inabil- ity in most patients to perform radical enough surgery in order to achieve clear margins, high morbidity of complete extirpation and limited response to radiotherapy or chemotherapy. How- ever, if complete surgical resection is possible, patients should be treated aggressively with a combination of surgery and adjuvant radiotherapy." @default.
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- W2600705325 date "2015-01-01" @default.
- W2600705325 modified "2023-09-23" @default.
- W2600705325 title "Locally Advanced Anaplastic Thyroid Carcinoma with Long-Term Survival of More Than 7 Years after Combined Surgery Including Tracheal Resection and Radiotherapy: Case Report" @default.
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- W2600705325 doi "https://doi.org/10.4172/2161-119x.1000197" @default.
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