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• W2600835737 abstract "Abstract Participant registries are repositories of individuals who have expressed willingness to learn about studies for which they may be eligible. Registries are increasingly being used to improve recruitment to preclinical Alzheimer's disease (AD) clinical trials, which require large screening efforts to identify adequate numbers of participants who meet enrollment criteria. Recruiting to preclinical AD trials from registries is made more efficient through registry collection of data that permits exclusion of those who will not be eligible and identifies individuals most likely to qualify for trials. Such data could include self‐reported disease family history or other risk factors but could also include cognitive, genetic, or biomarker testing outcomes. Few data are available to guide investigators overseeing registries and important ethical questions are likely to arise related to their conduct, especially in registries collecting AD risk information. This article outlines three areas of consideration for registry investigators: informed consent, disclosure, and sponsorship." @default.
• W2600835737 created "2017-04-07" @default.
• W2600835737 creator A5059549486 @default.
• W2600835737 date "2017-03-13" @default.
• W2600835737 modified "2023-09-30" @default.
• W2600835737 title "Recruiting to preclinical Alzheimer's disease clinical trials through registries" @default.
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• W2600835737 doi "https://doi.org/10.1016/j.trci.2017.02.004" @default.
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