Matches in SemOpenAlex for { <https://semopenalex.org/work/W2600984598> ?p ?o ?g. }
- W2600984598 abstract "New macromolecules such as dendrimers are increasingly needed to drive breakthroughs in diverse areas, for example, healthcare. Here, the authors report hybrid antimicrobial dendrimers synthesized by functionalizing organometallic dendrimers with quaternary ammonium groups or 2‐mercaptobenzothiazole. The functionalization tunes the glass transition temperature and antimicrobial activities of the dendrimers. Electron paramagnetic resonance spectroscopy reveals that the dendrimers form free radicals, which have significant implications for catalysis and biology. In vitro antimicrobial assays indicate that the dendrimers are potent antimicrobial agents with activity against multidrug‐resistant pathogens such as methicillin‐resistant Staphylococcus aureus and vancomycin‐resistant Enterococcus faecium as well as other microorganisms. The functionalization increases the activity, especially in the quaternary ammonium group‐functionalized dendrimers. Importantly, the activities are selective because human epidermal keratinocytes cells and BJ fibroblast cells exposed to the dendrimers are viable after 24 h. image" @default.
- W2600984598 created "2017-04-07" @default.
- W2600984598 creator A5001040554 @default.
- W2600984598 creator A5002155410 @default.
- W2600984598 creator A5034548897 @default.
- W2600984598 creator A5059036153 @default.
- W2600984598 creator A5067050526 @default.
- W2600984598 creator A5071221458 @default.
- W2600984598 creator A5073538833 @default.
- W2600984598 creator A5086992858 @default.
- W2600984598 date "2017-03-31" @default.
- W2600984598 modified "2023-10-06" @default.
- W2600984598 title "Quaternized and Thiazole-Functionalized Free Radical-Generating Organometallic Dendrimers as Antimicrobial Platform against Multidrug-Resistant Microorganisms" @default.
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- W2600984598 doi "https://doi.org/10.1002/mabi.201700020" @default.