Matches in SemOpenAlex for { <https://semopenalex.org/work/W2600988919> ?p ?o ?g. }
- W2600988919 endingPage "908" @default.
- W2600988919 startingPage "903" @default.
- W2600988919 abstract "The first example of simple nanoaggregates, self-assembled from a new class of polymer has been explored. The synthesis and characterization of polyethylene glycol and doxorubicin attached to a 1,6-heptadiyne derivative (Macromonomer) are clearly described. Macromonomer is polymerized via olefin metathesis living cyclopolymerization method using the Grubbs-Hoveyda catalyst to produce a water-soluble Dox-Peg-Rcp-Fmoc polymer. All of the monomers and polymers are carefully characterized by GPC and 1H NMR spectroscopy. Fmoc deprotection of the Dox-Peg-Rcp-Fmoc polymer is carried out to produce the Dox-Peg-Rcp polymer. The newly designed Dox-Peg-Rcp polymer shows nanoaggregation in water. In addition to that, they are soluble in water as well as biological media. The drug release profile at mild acidic condition shows the importance of having ester linker. CLSM images of Dox-Peg-Rcp nanoaggregates clearly show the efficient internalization into the living cells. MTT assays of Dox-Peg-Rcp nanoaggregates show t..." @default.
- W2600988919 created "2017-04-07" @default.
- W2600988919 creator A5025635629 @default.
- W2600988919 creator A5035606734 @default.
- W2600988919 creator A5053474619 @default.
- W2600988919 creator A5053899546 @default.
- W2600988919 creator A5068142139 @default.
- W2600988919 date "2017-04-14" @default.
- W2600988919 modified "2023-10-14" @default.
- W2600988919 title "Engineering a New Class of Multiarm Homopolymer for Sustainable Drug Delivery" @default.
- W2600988919 cites W1489417672 @default.
- W2600988919 cites W1666135105 @default.
- W2600988919 cites W181746683 @default.
- W2600988919 cites W1856773704 @default.
- W2600988919 cites W1924007993 @default.
- W2600988919 cites W1967783444 @default.
- W2600988919 cites W1975562526 @default.
- W2600988919 cites W1989362897 @default.
- W2600988919 cites W2002516695 @default.
- W2600988919 cites W2003299492 @default.
- W2600988919 cites W2011584091 @default.
- W2600988919 cites W2013470095 @default.
- W2600988919 cites W2013980860 @default.
- W2600988919 cites W2015403265 @default.
- W2600988919 cites W2017751632 @default.
- W2600988919 cites W2022745514 @default.
- W2600988919 cites W2022874479 @default.
- W2600988919 cites W2024295995 @default.
- W2600988919 cites W2024787650 @default.
- W2600988919 cites W2029629786 @default.
- W2600988919 cites W2030855909 @default.
- W2600988919 cites W2033410580 @default.
- W2600988919 cites W2034173691 @default.
- W2600988919 cites W2040273584 @default.
- W2600988919 cites W2043748429 @default.
- W2600988919 cites W2044743473 @default.
- W2600988919 cites W2057112987 @default.
- W2600988919 cites W2072247408 @default.
- W2600988919 cites W2073050103 @default.
- W2600988919 cites W2081766886 @default.
- W2600988919 cites W2086579182 @default.
- W2600988919 cites W2106390039 @default.
- W2600988919 cites W2106574596 @default.
- W2600988919 cites W2107092681 @default.
- W2600988919 cites W2130489277 @default.
- W2600988919 cites W2142721038 @default.
- W2600988919 cites W2164870487 @default.
- W2600988919 cites W2317172439 @default.
- W2600988919 cites W2321275568 @default.
- W2600988919 cites W2330231495 @default.
- W2600988919 cites W2399080566 @default.
- W2600988919 cites W2465805743 @default.
- W2600988919 cites W2500979903 @default.
- W2600988919 cites W2536309249 @default.
- W2600988919 cites W2540227434 @default.
- W2600988919 cites W2546806299 @default.
- W2600988919 cites W2561627084 @default.
- W2600988919 cites W2952848839 @default.
- W2600988919 cites W4240563364 @default.
- W2600988919 doi "https://doi.org/10.1021/acsbiomaterials.7b00100" @default.
- W2600988919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33429562" @default.
- W2600988919 hasPublicationYear "2017" @default.
- W2600988919 type Work @default.
- W2600988919 sameAs 2600988919 @default.
- W2600988919 citedByCount "15" @default.
- W2600988919 countsByYear W26009889192017 @default.
- W2600988919 countsByYear W26009889192018 @default.
- W2600988919 countsByYear W26009889192019 @default.
- W2600988919 countsByYear W26009889192020 @default.
- W2600988919 countsByYear W26009889192021 @default.
- W2600988919 countsByYear W26009889192022 @default.
- W2600988919 crossrefType "journal-article" @default.
- W2600988919 hasAuthorship W2600988919A5025635629 @default.
- W2600988919 hasAuthorship W2600988919A5035606734 @default.
- W2600988919 hasAuthorship W2600988919A5053474619 @default.
- W2600988919 hasAuthorship W2600988919A5053899546 @default.
- W2600988919 hasAuthorship W2600988919A5068142139 @default.
- W2600988919 hasConcept C126348684 @default.
- W2600988919 hasConcept C154945302 @default.
- W2600988919 hasConcept C171250308 @default.
- W2600988919 hasConcept C192562407 @default.
- W2600988919 hasConcept C2777212361 @default.
- W2600988919 hasConcept C2779820397 @default.
- W2600988919 hasConcept C2780035454 @default.
- W2600988919 hasConcept C41008148 @default.
- W2600988919 hasConcept C71924100 @default.
- W2600988919 hasConcept C98274493 @default.
- W2600988919 hasConceptScore W2600988919C126348684 @default.
- W2600988919 hasConceptScore W2600988919C154945302 @default.
- W2600988919 hasConceptScore W2600988919C171250308 @default.
- W2600988919 hasConceptScore W2600988919C192562407 @default.
- W2600988919 hasConceptScore W2600988919C2777212361 @default.
- W2600988919 hasConceptScore W2600988919C2779820397 @default.
- W2600988919 hasConceptScore W2600988919C2780035454 @default.
- W2600988919 hasConceptScore W2600988919C41008148 @default.
- W2600988919 hasConceptScore W2600988919C71924100 @default.
- W2600988919 hasConceptScore W2600988919C98274493 @default.
- W2600988919 hasFunder F4320334771 @default.