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- W2601082929 abstract "Drug resistance of bacterial pathogens is a growing problem that can be addressed through the discovery of compounds with novel mechanisms of antibacterial activity. Natural products, including plant phenolic compounds, are one source of diverse chemical structures that could inhibit bacteria through novel mechanisms. However, evaluating novel antibacterial mechanisms of action can be difficult and is uncommon in assessments of plant phenolic compounds. With systems biology approaches, though, antibacterial mechanisms can be assessed without the bias of target-directed bioassays to enable the discovery of novel mechanism(s) of action against drug resistant microorganisms. This review article summarizes the current knowledge of antibacterial mechanisms of action of plant phenolic compounds and discusses relevant methodology." @default.
- W2601082929 created "2017-04-07" @default.
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- W2601082929 date "2017-03-16" @default.
- W2601082929 modified "2023-10-11" @default.
- W2601082929 title "The Potential of Systems Biology to Discover Antibacterial Mechanisms of Plant Phenolics" @default.
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- W2601082929 doi "https://doi.org/10.3389/fmicb.2017.00422" @default.
- W2601082929 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5352675" @default.
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- W2601082929 hasPublicationYear "2017" @default.
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